Results 241 to 250 of about 270,928 (312)

A novel multiplex approach for the comprehensive analysis of the Epstein-Barr virus-specific humoral immune response. [PDF]

Front Cell Infect Microbiol
Meindl C, Weggel R, Deichl K, Fleischer KM, Hofmeier P, Last M, Nückel J, Planatscher E, Onsi LA, Schütt A, Behrends U, Mautner J.   +11 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

Low effectiveness of influenza vaccines vis-à-vis mechanism of protection by vaccines - potential causes and recommendations to improve control of influenza. [PDF]

Front Immunol
Gupta RK, Alugupalli KR, Cowell JL.
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Impact of oncogenic viruses on autoimmune diseases and tumorigenesis. [PDF]

Infect Agent Cancer
Hamidi Sofiani V, Khodadadpour Mahani F, Farsiu N, Yousefi M, Naderi M, Ahmadi G, Nakhaie M.   +6 more
europepmc   +1 more source

Dengue-specific T-cell memory following natural infection: a comparative analysis between people living with HIV and HIV-negative individuals. [PDF]

Microbiol Spectr
Lombardi F, Abatino A, Salvo PF, Aversa I, Baldin G, Gallo R, Tamburrini E, Laurenti P, Campolattano V, Giambenedetto SD, Torti C, Palmieri C.   +11 more
europepmc   +1 more source

Mucosal Vaccine Development: From Adjuvant Design to Next-Generation Delivery Strategies. [PDF]

Biomedicines
Lee WH, Kim E.
europepmc   +1 more source

Vaccines as treatment for melanoma: an update review. [PDF]

Front Immunol
Zhang J, Cao Q, Cen Y, Zhang L, Chen J.
europepmc   +1 more source

Epstein-Barr virus-associated multiple sclerosis: recent mechanistic advances and clinical therapeutic perspectives. [PDF]

Front Immunol
Cheng R, Gao Y, Zheng R, Wen M, Li G, Pan W, Liao Y, Wen L, Hu Y, Zhao-Fleming H, Shang P.   +10 more
europepmc   +1 more source