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Thymus dependence of viral antigens

Nature, 1975
AFTER exposure of animals to most antigens, formation of antibody by cells of the B lymphocyte lineage requires helper effects of T lymphocytes1. The degree of thymus dependence varies for different antigens, and slowly metabolised immunogens with repeating epitopes, generally polysaccharides or polymerised forms of protein, seem to be the most thymus ...
Burns, W H, Billups, L C, Notkins, A L
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Viral effects on antigen processing

Current Opinion in Immunology, 1999
Viruses have evolved numerous mechanisms that modulate MHC-mediated antigen presentation, which in turn protect infected cells from T-lymphocyte-mediated immunosurveillance. Recent studies of previously identified viral immunomodulatory proteins reveal the allelic specificity of these proteins, their ability to function in xenogeneic systems and the ...
D M, Miller, D D, Sedmak
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Viral interference with antigen presentation

Nature Immunology, 2002
CD8+ T cells play an important role in immunity to viruses. Just how important these cells are is demonstrated by the evolution of viral strategies for blocking the generation or display of peptide-major histocompatibility complex class I complexes on the surfaces of virus-infected cells.
Jonathan W, Yewdell, Ann B, Hill
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FÆCAL ANTIGEN IN VIRAL HEPATITIS

The Lancet, 1970
Abstract An antigen has been detected in faecal extracts from 90 out of 220 patients with viral hepatitis and from 5 of 158 patients with other diseases. In viral hepatitis this antigen is present early in the disease and usually disappears within three weeks of the first appearance of dark urine.
A A, Ferris   +3 more
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Australia Antigen and Acute Viral Hepatitis

Annals of Internal Medicine, 1969
Abstract Australia antigen (Au(1)) was found in the sera of 20% of 125 patients with acute viral hepatitis.
W T, London, A I, Sutnick, B S, Blumberg
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