Results 121 to 130 of about 2,390,491 (336)

Differential cytokine response of Escherichia coli lipopolysaccharide stimulated peripheral blood mononuclear cells in crossbred cattle, Tharparkar cattle and Murrah buffalo - An in vitro study

Spanish Journal of Agricultural Research, 2019
Mastitis is a complex disease responsible for huge economic losses to the dairy sector. The causal organisms include a wide variety of micro-organisms including several species of bacteria.
Sourabh Sulabh, Manjit Panigrahi, Satish Kumar, Rajat Varshney, Ankita Verma, Naseer A. Baba, Jay P. Gupta, Anuj Chauhan, Pushpendra Kumar, Triveni Dutt, Bharat Bhushan   +10 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Morphofunctional parameters of the immune system of chickens after dissemination of bacteria Pseudomonas aeruginosa

RUDN Journal of Agronomy and Animal Industries
Infectious diseases caused by ubiquitous bacteria with variability of virulence factors and multiple antibiotic resistance reliably often represent the structure of the general pathology of poultry.
Ekaterina M. Lenchenko, Galina S. Tolmacheva, Evgeny V. Kulikov   +2 more
doaj   +1 more source

HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers [PDF]

, 2010
The search for novel tumour antigens that are either uniquely expressed or over-expressed in a wide variety of tumours is still ongoing. Because of their expression in a broad spectrum of cancers and limited expression in normal tissues, cancer/testis ...
Badoual, C, Linley, AJ, Mathieu, MG, McArdle, SEB, Reeder, SP, Rees, RC, Tartour, E   +6 more
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Recombinant subunit vaccines against Neospora caninum [PDF]

, 2007
The intracellular protozoan parasite Neospora caninum is an important cause of bovine abortion and congenital infection in many countries. Currently there is no effective control method available, and development of a vaccine has been suggested as a ...
Pinitkiatisakul, Sunan
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Evolution of melanoma cross-resistance to CD8+ T cells and MAPK inhibition in the course of BRAFi treatment

OncoImmunology, 2018
The profound but frequently transient clinical responses to BRAFV600 inhibitor (BRAFi) treatment in melanoma emphasize the need for combinatorial therapies.
Natalia Pieper, Anne Zaremba, Sonia Leonardelli, Franziska Noelle Harbers, Marion Schwamborn, Silke Lübcke, Barbara Schrörs, Jolanthe Baingo, Alexander Schramm, Sebastian Haferkamp, Ulrike Seifert, Antje Sucker, Volker Lennerz, Thomas Wölfel, Dirk Schadendorf, Bastian Schilling, Annette Paschen, Fang Zhao   +17 more
doaj   +1 more source

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES [PDF]

, 1973
Alan S. Rosenthal, Ethan M. Shevach
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source