Results 311 to 320 of about 2,327,717 (363)

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source

Advances in the Functionalization of Vaccine Delivery Systems: Innovative Strategies and Translational Perspectives. [PDF]

Pharmaceutics
de Moura IA, Silva AJD, de Macêdo LS, Melo KMTB, Leal LRS, Espinoza BCF, Invenção MDCV, Pinho SS, Freitas AC.   +8 more
europepmc   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

Advanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng, Xuemei Zhong, Lu Deng, Xinling He, Miaoxizi Luo, Ruibing Wang, Jinming Zhang   +6 more
wiley   +1 more source

Correction to "Expression of Cancer-Testis Antigens MAGE-A1, MAGE-A4, NY-ESO-1 and PRAME in Bone and Soft Tissue Sarcomas: The Experience From a Single Center in China". [PDF]

Cancer Med
europepmc   +1 more source

Retrospective analysis of sex-disaggregated immune responses to ALVAC-HIV and bivalent subtype C gp120/MF59 HIV vaccines. [PDF]

Front Immunol
Ackerley CG, Edupuganti S, Yu C, Roxby AC, Seaton KE, Bekker LG, Allen M, DeRosa SC, Yates NL, Heptinstall J, Mkhize NN, Malahleha M, Mngadi K, Daniels B, Innes C, Furch BD, Koutsoukos M, Ferrari G, Morris L, Montefiori DC, McElrath MJ, Tomaras GD, Laher F, Moodie Z.   +23 more
europepmc   +1 more source

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

Advanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing, Ke Jiang, Hua Jiang, Yaru Zhao, Chu‐Hu Lai, Alexandra Aicher, Zonghai Li, Christopher Heeschen   +7 more
wiley   +1 more source

Administration of Trichinella spiralis Antigens Alleviated Diabetic Nephropathy in Diabetic Mice. [PDF]

Acta Parasitol
El-Kady AM, Altwaim SA, Albohiri HH, Wakid MH, Mohamed K, Alshehri EA, Elshazly H, Elshabrawy HA, Hamed D.   +8 more
europepmc   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source

Design of a multi-epitope vaccine candidate against Vibrio cholerae. [PDF]

Sci Rep
Koupaei FN, Kiumarsy A, Feizi MM, Vajdi Z, Edalat Pishkar S, Alem M, Roohparvar Basmenj E.   +6 more
europepmc   +1 more source

Geometric Adjustment of T Cell‐Sensitive Nanorobots for Enhanced Stability

Advanced Healthcare Materials, EarlyView.
For the long‐term use of live dendritic cell (DC)‐based vaccines, nano bone marrow dendritic cell (BMDC) originated T cell activators (nano‐BOTs) are synthesized. The geometric properties of nanoparticles are precisely modulated, enhancing their stability and T cell activation capacity.
Yoojin Lee, Dahae Kim, Taihyun Kim, Chae‐Won Moon, Hyungseok Yong, Sung‐eun Heo, Bumgyu Choi, Yoogyeong Oh, Woojin Choi, Kyungtae Park, Sang‐Jun Ha, Jinkee Hong   +11 more
wiley   +1 more source