Results 11 to 20 of about 74,021 (384)

Can Twitter be a source of information on allergy? Correlation of pollen counts with tweets reporting symptoms of allergic rhinoconjunctivitis and names of antihistamine drugs [PDF]

open access: yesPLoS ONE, 2015
Pollen forecasts are in use everywhere to inform therapeutic decisions for patients with allergic rhinoconjunctivitis (ARC). We exploited data derived from Twitter in order to identify tweets reporting a combination of symptoms consistent with a case ...
Carloni, E   +7 more
core   +2 more sources

Metabolomic insights into variable antihistamine responses in allergic rhinitis: unveiling biomarkers for precision treatment [PDF]

open access: yesFrontiers in Immunology
BackgroundThe clinical response to antihistamine therapy exhibits substantial heterogeneity among individuals with allergic rhinitis (AR). While these medications represent a cornerstone in AR management, the molecular basis underlying differential ...
Xiaohong Lyu   +11 more
doaj   +2 more sources

The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria [PDF]

open access: yesActa Dermato-Venereologica
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predictors
Yingyi Li   +3 more
doaj   +2 more sources

Fenebrutinib in H1 antihistamine-refractory chronic spontaneous urticaria: a randomized phase 2 trial

open access: yesNature Medicine, 2021
Bruton’s tyrosine kinase (BTK) is crucial for FcεRI-mediated mast cell activation and essential for autoantibody production by B cells in chronic spontaneous urticaria (CSU).
M. Metz   +15 more
semanticscholar   +1 more source

Structural basis for recognition of antihistamine drug by human histamine receptor

open access: yesNature Communications, 2022
The histamine receptors belong to the G protein-coupled receptor (GPCR) superfamily, and play important roles in the regulation of histamine and other neurotransmitters in the central nervous system, as potential targets for the treatment of neurologic ...
Xueqian Peng   +7 more
semanticscholar   +1 more source

Antihistamine‐related deaths in England: Are the high safety profiles of antihistamines leading to their unsafe use?

open access: yesBritish Journal of Clinical Pharmacology, 2021
Antihistamines are routinely taken to control allergic reactions or sedation to induce sleep. There are, however, growing concerns regarding sedating antihistamine misuse.
P. J. Oyekan, H. Gorton, C. Copeland
semanticscholar   +1 more source

Influence of the H1 Antihistamine Mepyramine on the Antibacterial Effect of Florfenicol in Pigs

open access: yesVeterinary Sciences, 2021
The effect of florfenicol against Escherichia coli (E. coli) was investigated in vivo to confirm results of an in vitro study of Bruer et al. (2019), which has shown positive effects of various antibacterial agents in combination with the antihistamine ...
Gustav G. Bruer   +3 more
doaj   +1 more source

Use of H-1 Antihistamine in Dermatology: More than Itch and Urticaria Control: A Systematic Review

open access: yesDermatologic Therapy, 2021
H-1 antihistamines are commonly used in dermatological practice for itch and urticaria control. The widespread expression of H-1 receptor on different cells in the skin and various biologic functions of H-1 antihistamines indicate the possible treatment ...
Chang-Yu Hsieh, T. Tsai
semanticscholar   +1 more source

Antihistamine use during breastfeeding with focus on breast milk transfer and safety in humans: A systematic literature review

open access: yesBasic & Clinical Pharmacology & Toxicology, 2021
Current data on use of antihistamines during breastfeeding and risks to the breastfed infant are insufficient. The aim of this systematic review was to provide an overview of studies measuring the levels of antihistamines in human breast milk, estimating
Elin Ngo   +6 more
semanticscholar   +1 more source

Ameliorative Effect of a Neoteric Regimen of Catechin plus Cetirizine on Ovalbumin-Induced Allergic Rhinitis in Rats

open access: yesLife, 2022
Allergic rhinitis (AR) affects 20–50% of the global population. Available treatments are limited by their adverse effects. We investigated the anti-allergic effects of catechin alone and combined with cetirizine against ovalbumin-induced AR.
Mohamed A. Morsy   +7 more
doaj   +1 more source

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