Results 71 to 80 of about 71,170 (384)

Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi   +7 more
wiley   +1 more source

Effect of histamine‐receptor antagonism on the circulating inflammatory cell and cytokine response to exercise: A pilot study

open access: yesPhysiological Reports
The purpose of this study was to gain insight into histamine's role in the exercise inflammatory response and recovery from exercise. To explore this, young healthy participants (n = 12) performed 300 eccentric leg extensions under control (Placebo ...
Matthew R. Ely   +4 more
doaj   +1 more source

Histamine Regulates Molecular Clock Oscillations in Human Retinal Pigment Epithelial Cells via H1 Receptors

open access: yesFrontiers in Endocrinology, 2018
Vertebrate eyes are known to contain circadian clocks, but their regulatory mechanisms remain largely unknown. To address this, we used a cell line from human retinal pigment epithelium (hRPE-YC) with stable coexpression of reporters for molecular clock ...
Eri Morioka   +4 more
doaj   +1 more source

Carbon nanotube modified glassy carbon electrode for electrochemical oxidation of alkylphenol ethoxylate [PDF]

open access: yes, 2018
Electrochemical oxidation of an emerging pollutant, 2-(4-methylphenoxy)ethanol (MPET), from water has been studied by cyclic voltammetry (CV). Multiwall carbon nanotubes glassy carbon electrodes (MWCNT-GCE) were used as working electrode due to their ...
Díaz Fernández, Eva   +3 more
core   +2 more sources

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano   +8 more
wiley   +1 more source

Actual antihistamine therapy

open access: yesМедицинский совет, 2020
The significance of the issues of allergic diseases is not in doubt. It is difficult to find a person who has not suffered at least some Allergy symptom, not everyone develops diseases, but most people face Allergy symptoms.
D. V. Shabanov, Ju. E. Lutkovskaya
doaj   +1 more source

Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]

open access: yes, 2008
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
B. Przybilla   +9 more
core   +1 more source

Rupatadine: efficacy and safety of a non-sedating antihistamine with PAF-antagonist effects

open access: yesAllergo Journal International, 2014
SummaryRupatadine is a modern non-sedating H1-antihistamine that also haswith additional antagonist effects on platelet-activating factor (PAF). Under the tradenames Rupafin® and Urtimed®, Rrupatadine is approvedregistered in Germany for the treatment of
Soja Shamizadeh, K. Brockow, J. Ring
semanticscholar   +1 more source

Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry

open access: yesDrug Testing and Analysis, EarlyView.
In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain in the laboratory, for example, in terms of calibrator solution preparation. A fast, simple, and robust liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification of 82 classic ...
Andrea E. Steuer   +3 more
wiley   +1 more source

Rhinitis in general practice [PDF]

open access: yes, 2007
A 3 year old boy presented with a 3 week history of nasal obstruction, clear rhinorrhea, difficulty with feeding and a productive cough. Child was afebrile, had occasional watery itchy eyes and mother claimed that at night he tended to wake up a couple ...
drkvassallo@yahoo.co.uk   +1 more
core  

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