Results 201 to 210 of about 9,174 (251)
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2014
The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
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The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
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Journal of Allergy and Clinical Immunology, 1989
Substantial evidence indicates that airway hyperresponsiveness in asthma is associated with the inflammatory response directed toward the airway epithelium and submucosa. Endogenously released spasmogenic mediators interacting with smooth muscle have a greater effect on hyperresponsive than on normal airways.
S T, Holgate, J P, Finnerty
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Substantial evidence indicates that airway hyperresponsiveness in asthma is associated with the inflammatory response directed toward the airway epithelium and submucosa. Endogenously released spasmogenic mediators interacting with smooth muscle have a greater effect on hyperresponsive than on normal airways.
S T, Holgate, J P, Finnerty
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2015
Histamine is one of the best-characterized pruritogens in humans. It is known to play a role in pruritus associated with urticaria as well as ocular and nasal allergic reactions. Histamine mediates its effect via four receptors. Antihistamines that block the activation of the histamine H₁receptor, H₁R, have been shown to be effective therapeutics for ...
Robin L, Thurmond +3 more
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Histamine is one of the best-characterized pruritogens in humans. It is known to play a role in pruritus associated with urticaria as well as ocular and nasal allergic reactions. Histamine mediates its effect via four receptors. Antihistamines that block the activation of the histamine H₁receptor, H₁R, have been shown to be effective therapeutics for ...
Robin L, Thurmond +3 more
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Journal of the American Medical Association, 1947
Any medicament, no matter how valuable, may do great harm if it is employed indiscriminately. The fame of the new antihistaminic drugs has become so widespread, indeed, that they are often prescribed merely to satisfy the patient's curiosity. A critical inventory of their value is therefore indicated.
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Any medicament, no matter how valuable, may do great harm if it is employed indiscriminately. The fame of the new antihistaminic drugs has become so widespread, indeed, that they are often prescribed merely to satisfy the patient's curiosity. A critical inventory of their value is therefore indicated.
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Hypersensitivity to antihistamines
Allergy and Asthma Proceedings, 2013Antihistamines are the cornerstone of allergy therapy and are not expected to cause hypersensitivity reactions. We describe two cases, one had urticaria to multiple anti-H1-preparations and the other had anaphylaxis to hydroxyzine. We also provide a review of the English literature on reported reactions regarding causative preparations and ...
Alireza A, Shakouri, Sami L, Bahna
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Clinical & Experimental Allergy, 1999
Urticaria is one of the most common and, in its chronic course, excruciating dermato‐allergic diseases. Apart from the dermatological diagnosis, the identification and evaluation of causal triggering factors is of utmost importance. Here a ‘three‐step guideline’ (according to Ring and Przybilla) has gained acceptance, ranging from a general basic ...
J, Ring, K, Brockow, M, Ollert, R, Engst
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Urticaria is one of the most common and, in its chronic course, excruciating dermato‐allergic diseases. Apart from the dermatological diagnosis, the identification and evaluation of causal triggering factors is of utmost importance. Here a ‘three‐step guideline’ (according to Ring and Przybilla) has gained acceptance, ranging from a general basic ...
J, Ring, K, Brockow, M, Ollert, R, Engst
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Acta Physiologica Scandinavica, 1949
Summary.Cats were treated with doses of legation intravenously that suppressed the blood pressure action of moderate histamine doses. The responses of respiration to inhalation of gas mixtures poor in oxygen or rich in carom dioxide were undiminished.
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Summary.Cats were treated with doses of legation intravenously that suppressed the blood pressure action of moderate histamine doses. The responses of respiration to inhalation of gas mixtures poor in oxygen or rich in carom dioxide were undiminished.
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Annals of Otology, Rhinology & Laryngology, 1976
Antihistamines may be used to maximum benefit for the allergic patient if the physician adheres to four guidelines. These guidelines are based upon 1) an appreciation of certain structural and pharmacologic differences among antihistamines, and 2) an understanding of their mechanism of action.
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Antihistamines may be used to maximum benefit for the allergic patient if the physician adheres to four guidelines. These guidelines are based upon 1) an appreciation of certain structural and pharmacologic differences among antihistamines, and 2) an understanding of their mechanism of action.
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Journal of Clinical Pharmacy and Therapeutics, 2001
Histamine activates pain-transmitting nerve fibres, releases pain-related neuropeptides, and is painful when injected into the skin. Histamine agonists mimic these effects, suggesting that histamine plays a role in mediating the signal transduction of tissue damage or other painful stimulus.
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Histamine activates pain-transmitting nerve fibres, releases pain-related neuropeptides, and is painful when injected into the skin. Histamine agonists mimic these effects, suggesting that histamine plays a role in mediating the signal transduction of tissue damage or other painful stimulus.
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Tuberculosis and Antihistaminics
Diseases of the Chest, 19491) The present knowledge of antihistaminics, particularly the pharmacologic considerations are presented. 2) Tuberculous allergy and tuberculous anaphylaxis are presented as widely different mechanisms and carefully differentiated. 3) Neo-Antergan and phenergan (RP3277) were given for several months in a series of thirty patients with ...
T, MILLNER, A, HURST
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