Results 181 to 190 of about 9,174 (251)

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Aseptic meningitis due to intravenous immunoglobulin therapy (IVIG) in therapy‐refractory pyoderma gangraenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber, Knut Schäkel, Alexander Enk, Julia K. Winkler   +3 more
wiley   +1 more source

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

Hip Fracture Risk of Lemborexant and Suvorexant in Comparison With Z‐Drugs: A Target Trial Emulation

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Lemborexant and suvorexant are widely used dual orexin receptor antagonists (DORAs) for the pharmacological treatment of insomnia. Although they are generally considered safer than benzodiazepine receptor agonists (Z‐drugs) regarding adverse events including hip fractures, evidence from direct comparisons remains limited. This study
Yuichiro Matsuo, Hayato Yamana, Yusuke Sasabuchi, Hiroki Matsui, Takahide Kohro, Hideo Yasunaga   +5 more
wiley   +1 more source

Nemolizumab for Pruritus Control in Cutaneous T‐Cell Lymphoma: A Case Series

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Yenny Angela, Ralf Gutzmer, Rudolf Stadler   +2 more
wiley   +1 more source

Dynamic Pressure Ulcer Risk Predictions for Hospitalized Patients: Development and Validation of a Machine Learning Model With Nurses

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To develop and validate a dynamic prediction model for daily pressure ulcer risk predictions together with an expert group of nurses. Design Diagnostic study. Methods All admissions to general wards in a single‐center tertiary university hospital in the Netherlands were included.
Steffen Greup, Denise Spoon, Annemarie de Vroed, Ben Werkhoven, Enrico Timmerman, Monique van Dijk, Erwin Ista   +6 more
wiley   +1 more source

Cancer co‐medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care

Journal of Internal Medicine, EarlyView.
Abstract Background Evidence from randomized controlled trials (RCTs) testing medication reviews in geriatric oncology is sparse. Methods We conducted a single‐blinded RCT in ten rehabilitation clinics across Germany. Patients with common cancers, aged ≥ 65 years, and polypharmacy (regularly ≥ five drugs) were randomly allocated in equal proportions to
Miriam Degen, Annette Kopp‐Schneider, Tomislav Vlaski, Sigrid Carlsson, Peter Hallermann, Ludmilla Jewlanowa, Jana Barinoff, Valentin Goede, Christian Lüders, Thomas Kiefer‐Trendelenburg, Diana Lüftner, Jasmin Doll, Jürgen Wagner, Birgit Leibbrand, Hermann Brenner, Ben Schöttker   +15 more
wiley   +1 more source

Clinical Symptomatology, Cognition and Psychosocial Wellbeing in Adolescents With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Cross‐Sectional Observational Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling illness that frequently begins in adolescence, yet adolescents with ME/CFS remain an under‐researched population. We aimed to characterise the cognitive and psychosocial wellbeing of adolescents with ME/CFS relative to normative benchmarks and unaffected age‐peers ...
Tracey Chau, Elisha K. Josev, Adam Scheinberg, Natalie Thomas, Fiona McDonald, Colette Reveley, Paul R. Gooley, Christopher Armstrong, Sarah Knight   +8 more
wiley   +1 more source

Neurokinin‐1 receptor antagonist (maropitant) for treatment of chronic idiopathic rhinitis in dogs: a pilot study

Journal of Small Animal Practice, EarlyView.
Objectives Chronic idiopathic rhinitis is a common canine nasal disease with unknown aetiology and poor response to treatment. Neurokinin‐1 receptor activation has been associated with rhinitis in experimental animals. The aim of this pilot study was to compare the effects of oral neurokinin‐1 receptor antagonist (maropitant) with placebo on clinical ...
H. Neittaanmäki, M. Rajamäki, N. Airas, A. Tilamaa, S. Viitanen   +4 more
wiley   +1 more source