Results 31 to 40 of about 112,013 (216)
Permutation inference methods for multivariate meta-analysis [PDF]
Multivariate meta-analysis is gaining prominence in evidence synthesis research because it enables simultaneous synthesis of multiple correlated outcome data, and random-effects models have generally been used for addressing between-studies heterogeneities.
arxiv +1 more source
Modern combination antihypertensive pharmacotherapy [PDF]
Achievement of target blood pressure levels is one of the main issues in antihypertensive pharmacotherapy. The article presents updated 2018 European Guidelines recommendations on target blood pressure levels in antihypertensive therapy and combined ...
O A Mubarakshina+2 more
doaj +1 more source
A computational framework for pharmaco-mechanical interactions in arterial walls using parallel monolithic domain decomposition methods [PDF]
A computational framework is presented to numerically simulate the effects of antihypertensive drugs, in particular calcium channel blockers, on the mechanical response of arterial walls. A stretch-dependent smooth muscle model by Uhlmann and Balzani is modified to describe the interaction of pharmacological drugs and the inhibition of smooth muscle ...
arxiv
Combination therapy in the treatment of hypertension
Hypertension is a major preventable risk factor for atherosclerosis and ischemic heart disease. Although modern and effective antihypertensive drugs are available, most patients remain with a suboptimal blood pressure control.
Alberto Francisco Rubio-Guerra
doaj +1 more source
Antihypertensive agents are commonly prescribed to manage hypertension and are known to be beneficial for bone formation and remodeling. The aim of this systematic review was to assess the impact that antihypertensive agents have on dental implant ...
Dary Jones+4 more
doaj +1 more source
Patrones de uso de antihipertensivos en 11.947 pacientes colombianos.
El 12,6% de la población colombiana mayor de 15 años es hipertensa. Para conocer sobre el manejo farmacológico de la hipertensión y su comorbilidad, se desarrolló este estudio en 11.947 hipertensos adultos de ambos sexos, en tratamiento durante más de 3 ...
Carlos A. Isaza+3 more
doaj +1 more source
Inferring medication adherence from time-varying health measures [PDF]
Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful treatment outcomes and even preventable deaths.
arxiv
Doubly robust estimation and sensitivity analysis for marginal structural quantile models [PDF]
The marginal structure quantile model (MSQM) provides a unique lens to understand the causal effect of a time-varying treatment on the full distribution of potential outcomes. Under the semiparametric framework, we derive the efficiency influence function for the MSQM, from which a new doubly robust estimator is proposed for point estimation and ...
arxiv
Synthesis of Benzimidazole Derivatives: As Anti-hypertensive Agents
A new series of non peptide angiotensin(A-II) receptor antagonist has been prepared. This N-(biphenyl methyl) imidazoles e.g. 5-substituted (amino) -2- phenyl-1-(2ʼcarboxy biphenyl-4-yl) benzimidazoles differ from the previously reported and related ...
Jat Rakesh Kumar+2 more
doaj +1 more source
Gingival Enlargement in Antihypertensive Medication
Introduction: Drug-induced gingival enlargement is a well documented side effect with the use of phenytoin, cyclosporine and calcium channel blockers. The prevalence of gingival enlargement induced by calcium channel blockers is uncertain.
Shaili Pradhan, P Mishra
doaj +1 more source