Results 191 to 200 of about 87,717 (260)

Study of the Acidic, Basic, and Thermal Degradation Kinetics of Three Antihypertensive Drugs-Individually and in Combination. [PDF]

Pharmaceutics
Mandić-Kovacević N, Kasagić-Vujanović I, Gatarić B, Škrbić R, Popović Bijelić A.   +4 more
europepmc   +1 more source

Angiotensin Receptor Blockers Versus Calcium Channel Blockers for First‐Line Antihypertensive Therapy and Survival in Adults Aged 75 Years or Older

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Evidence guiding first‐line antihypertensive drug choice in adults aged 75 years or older is limited, despite widespread use of angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) in late older age. Methods We conducted a target trial emulation using a new‐user design in a nationwide linked healthcare claims ...
Hisashi Noma, Hiroshi Sunada, Taiki Sugimoto, Ken‐Ei Sada, Futoshi Oda, Megumi Maeda, Haruhisa Fukuda   +6 more
wiley   +1 more source

Causal relationship between antihypertensive drugs and Hashimoto's thyroiditis: a drug-target Mendelian randomization study. [PDF]

Front Endocrinol (Lausanne)
Cui B, Chen A, Xu C, Mao C, Chen Y.
europepmc   +1 more source

Assessing Associations of Three Types of Higher‐Risk Medication Use and Mortality in Older Adults

Journal of the American Geriatrics Society, EarlyView.
Having a medication regimen with polypharmacy was associated with higher risk of mortality among older adults even after accounting for clinical factors and other types of higher‐risk medication use. ABSTRACT Background Higher‐risk medication use—including regimens with polypharmacy, drug–drug interactions (DDIs), and potentially inappropriate ...
Alexander Chaitoff, Katharina Tabea Jungo, Lillian Min, Donovan T. Maust   +3 more
wiley   +1 more source

Two-Sample Network Mendelian Randomization and Single-Cell Analysis Reveal the Causal Associations and Underlying Mechanisms Between Antihypertensive Drugs and Kidney Cancer. [PDF]

J Cancer
Deng R, Zou M, Qiu J, Shang J, Yu C, Tian P, Wang Y, Cai L, Zhou J, Gong K.   +9 more
europepmc   +1 more source

Pharmacovigilance monitoring and treatment adherence in patients on antihypertensive drugs at a tertiary care centre. [PDF]

Drugs Context
Agrawal P, Patrick S, Thomas M, Gupta D, Singh Matreja P, Singh P, Zafar S.   +6 more
europepmc   +1 more source

Target Trial Emulation in Observational Research—Strengths, Limitations, and Methodological Considerations

Journal of Periodontal Research, EarlyView.
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister, Ignacio Leiva‐Escobar, Ryan T. Demmer, Panos N. Papapanou, Thomas Kocher, Birte Holtfreter, Michael Nolde   +6 more
wiley   +1 more source

Association between blood pressure traits, hypertension, antihypertensive drugs and calcific aortic valve stenosis: a mendelian randomization study. [PDF]

J Geriatr Cardiol
Lei WH, Zhang JL, Liao YB, Wang Y, Xu F, Zhang YY, Xu Y, Zhou J, Huang FY, Chen M.   +9 more
europepmc   +1 more source

Repurposing antihypertensive drugs for pain disorders: a drug-target mendelian randomization study. [PDF]

Front Pharmacol
Du K, Li A, Zhang CY, Li SM, Chen P.
europepmc   +1 more source

Impact of the COVID-19 pandemic on initiation of antihypertensive drugs in Sweden: an interrupted time series study. [PDF]

BMJ Open
Tomas A, Wettermark B, Nyberg F, Hajiebrahimi M.   +3 more
europepmc   +1 more source