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Antihypertensive drugs

Clinical Pharmacology & Therapeutics, 1962
Drug therapy for essential hypertension is now firmly established. Agents presently available, if used wisely, are capable of controlling hypertension in almost every patient requiring such treatment. There are certain important factors which must be carefully evaluated before patients are started on long‐term antihypertensive therapy.
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EFFICACY OF ANTIHYPERTENSIVE DRUGS

The Lancet, 1976
The magnitude of the fall in blood-pressure in response to an antihypertensive drug depends on the level of the pretreatment pressure, and there is a direct relationship between the two in that the higher the pretreatment pressure the greater the fall in pressure in response to treatment.
G T, Dixon, E S, Johnson
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Antihypertensive Drugs

American Journal of Cardiovascular Drugs, 2002
For most patients with systemic hypertension, long-term drug treatment is indicated and is beneficial. There is overwhelming evidence to suggest that antihypertensive drugs offer protection against complications of hypertension. Whereas nondrug therapeutic options should be implemented in all patients, a vast majority will require pharmacological ...
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Antihypertensive drugs and depression

Psychological Medicine, 1974
SYSNOPSISThe introduction of reserpine into western medical practice led to an outbreak of iatrogenic depression. It also stimulated research into the fundamental biochemical errors underlying depressive illness. In view of this historical incident it is surprising that other drugs used in the treatment of hypertension, especially those producing their
R P, Snaith, M, McCoubrie
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Antihypertensive Drugs in Pregnancy

Clinics in Perinatology, 1987
This article considers the pathophysiology, diagnosis, and etiologies of hypertensive conditions, and considers specific agents for treating this condition. It also reviews the side effects of these agents and their efficacy, and details their use in the hypertensive pregnant patient.
W, Doany, C R, Brinkman
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Newer Antihypertensive Drugs

Postgraduate Medicine, 1960
Even a little hypertension is a dangerous thing. The mortality and morbidity associated with this condition are now clearly apparent.Specific treatment for hypertension has been developed within th...
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Antihypertensive Drugs in Pregnancy

Clinics in Perinatology, 1985
When mean arterial pressure exceeds 140 mmHg (equivalent to 180/120), there is a significant risk of maternal cerebral vascular damage. Therefore it is recommended that blood pressures greater than 170/110 should be treated with urgency, aiming to maintain the blood pressure at all times at less than 170/110 but not lower than 130/90.
R P, Naden, C W, Redman
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ICP and Antihypertensive Drugs

2018
Arterial hypertension is among the leading risks for mortality. This burden requires in hypertensive patients the use of single, double or more antihypertensive drugs. The relationship between intracranial pressure (ICP) and arterial blood pressure is complex and still under debate. The impact of antihypertensive drugs on ICP is unknown.
Charlotte, Rouzaud-Laborde   +4 more
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Newer antihypertensive drugs

Current Opinion in CARDIOLOGY, 1995
We review three new classes of antihypertensive drugs: imidazolines, monatepil, and neutral endopeptidase inhibitors. Imidazolines are a new generation of central acting drugs. Because of their greater affinity for imidazoline receptors rather than alpha 2-adrenoreceptors, they cause less fatigue and dry mouth than the older central acting drugs ...
J R, Gregoire, S G, Sheps
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Pharmacology of Antihypertensive Drugs

Journal of Obstetric, Gynecologic & Neonatal Nursing, 1999
The wide variety of first-line agents available for managing high blood pressure include diuretics, beta adrenergic receptor blockers, alpha adrenergic receptor blockers, angiotensin converting enzyme inhibitors, and calcium channel blockers. Supplemental agents used for second-line therapy and special indications, such as pregnancy and hypertensive ...
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