Results 131 to 140 of about 80,047 (217)

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

Birth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim, Geum‐Sil Cho, Andreas Gado, Tobias Hyun Ho Baeurle, Habib Karimi, Filippo Venezia, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha, Claudia Demarta‐Gatsi   +9 more
wiley   +1 more source

Structural Characterization of 7-Chloro-4-(4-methyl-1-piperazinyl)quinoline Monohydrate

Molbank
The crystal structure of the hydrated form of 7-chloro-4-(4-methyl-1-piperazinyl)quinoline (BPIP) was determined by single-crystal X-ray diffraction analysis.
Silvia Rizzato, Francesco Marinoni
doaj   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Case Report: Recurrent Complicated Urinary Tract Infection in Prune Belly Syndrome With Solitary Functioning Kidney

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Recurrent UTIs in prune belly Syndrome with a markedly reduced renal function pose significant renal injury risk. Normal creatinine can mask underlying damage. Long‐term, multidisciplinary follow‐up is crucial, especially in low‐resource settings, to preserve renal function and improve patient outcomes.
Mohammed Elhadi Badawi Mahjoub, Shafee S. Almahi, Mohamed Jadain   +2 more
wiley   +1 more source

Impact of Sickle Cell Hemoglobin Genotypes on Clinical Outcomes Among Plasmodium falciparum Malaria Patients in Luanda, Angola

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Sickle cell anemia (SCA) may influence malaria susceptibility and clinical outcomes in endemic regions. However, the interaction between hemoglobin genotypes and malaria severity remain poorly defined in endemic African settings, particulary in Angola, where SCA and malaria impose a substantial public health burden.
Cruz S. Sebastião, Eduardo Ekundi‐Valentim, Edson Cassinela, Euclides Sacomboio   +3 more
wiley   +1 more source

Community‐Centric Malaria Prevention in Sub‐Saharan Africa: A Narrative Review of Pathways to Elimination and Global Health Impact

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Malaria remains a major global health challenge, with the World Health Organization (WHO) African Region accounting for the overwhelming majority of malaria cases and deaths worldwide. This narrative review examines the contribution of community‐centric malaria prevention approaches to malaria elimination pathways and their
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Assessing the Use of Oxford Nanopore Technologies Sequencing for Detection of Stable Wolbachia Bacterial Strain in Symbiosis in Wild Anopheles Mosquitoes From the WHO African Region

Environmental Microbiology, Volume 28, Issue 10, October 2026.
This study assesses Oxford Nanopore Technology sequencing to detect Wolbachia in Anopheles mosquitoes. To do this, samples were analysed using the ONT field sequencing kit and sequenced using a minION flow cell and the ONT 16S barcoding kit and Rapid barcoding kit sequenced using Flongle flow cells.
Laura Chatterley, Nicola Hull, Isabel Hughes, Seynabou Sougoufara, Owain Meek, Murat Ceyran, Vishaal Dhokiya, Janvier Bandibabone, Cyprian Adala, Elin Cunningham, Shehu Shagari Awandu, Helene Kaminski‐Nenkam, Antonio Nkondjio, Grant L. Hughes, Eva Heinz, Thomas Walker   +15 more
wiley   +1 more source

Compound antimalarial ethosomal cataplasm: preparation, evaluation, and mechanism of penetration enhancement

, 2015
Shuo Shen, Shu-Zhi Liu, Yu-Shi Zhang, Mao-Bo Du, Ai-Hua Liang, Li-Hua Song, Zu-Guang Ye Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China Abstract: Malaria is still a serious ...
Liang AH, Liu SZ, Ye ZG, Du MB, Shen S, Zhang YS, Song LH   +6 more
core  

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 887-892, October 2026.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source