Results 141 to 150 of about 113,882 (274)

Design and Synthesis of Some New Quinoline Based 1,2,3-Triazoles as Antimicrobial and Antimalarial Agents

Orbital: The Electronic Journal of Chemistry, 2015
A series of novel 6-bromo-2-chloro-3-(4-phenyl-[1,2,3]triazol-1-ylmethyl)-quinoline and its derivatives (5a-j) were synthesized in good yields from the intermediates (6-bromo-2-chloro-quinolin-3-yl)-methanol (2), methanesulfonic acid (6-bromo-2 ...
Parthasaradhi Y., Suresh S., Ranjith Kumar B., Savitha Jyostna T.   +3 more
doaj  

Substitutive Approach Toward Heteroaromatic Amino Alcohols Accessed Through Dioxolanyl Radical Linchpin

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
A dioxolanyl linchpin has been used to synthesize aryl ethanolamines from readily available aryl bromide and amine starting materials using a metallaphotoredox/substitution telescoped sequence. This combinatorial approach allows for a wide synthetic scope of both heteroarenes and cyclic amines. Aryl ethanolamines are an important functional group found
Justin J. Chang, Munnu Kumar, Ryan C. Kashatus, Dylan J. Tomaselli, Daniel K. Kim   +4 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

The Epidemiology of Sickle Cell Disease in Sub‐Saharan Africa: Current Knowledge and Gaps to be Filled

American Journal of Hematology, Volume 101, Issue S1, Page 5-16, April 2026.
What are the available data on incidence & prevalence prognosis risk factors of severity of sickle cell disease in sub‐Saharan Africa? ABSTRACT Sickle Cell Disease (SCD) is highly prevalent in sub‐Saharan Africa. Epidemiological data remain sparse, but regional screening and research initiatives are expanding.
Brigitte Ranque, Leon Tshilolo, Thomas N. Williams   +2 more
wiley   +1 more source

Gaps in knowledge and use of artemether-lumefantrine among university students in Southwestern Nigeria: A cross-sectional study. [PDF]

PLoS One
Orok E, Olumoko O, Ekada I, Oladunni A.
europepmc   +1 more source

Navigating Practical, Political, and Ethical Challenges of Long‐Term Human Biology Field Research: The Shuar Health and Life History Project

American Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT Major advances in understanding human biology and health have been made possible by long‐term field research projects with Indigenous peoples, whose ecological settings and lifeways are distinct from majority populations in high‐income settings.
J. Josh Snodgrass, Felicia C. Madimenos, Melissa A. Liebert, Samuel S. Urlacher, Tara J. Cepon‐Robins, Theresa E. Gildner, Richard G. Bribiescas, Lawrence S. Sugiyama   +7 more
wiley   +1 more source

Mechanistic perspectives on antimalarial agents: from FDA-approved drugs to next-generation candidates. [PDF]

RSC Adv
Monika, Sharma B, Awasthi SK.
europepmc   +1 more source

CBr4‐Mediated Metal‐Free Sulfonamide Synthesis: A Comparative Study Under Batch, Continuous‐Flow and Ultrasonic Conditions

Asian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.
A practical and efficient CBr4‐mediated metal‐free route for sulfonamide synthesis is presented under batch, ultrasonic, and continuous‐flow conditions. The protocol demonstrates excellent substrate scope, reduced reaction times, and mild operating conditions, highlighting a scalable alternative to traditional iodine‐mediated methods in modern ...
Alageswaran Jayaram, Vijay Thavasianandam Seenivasan, Yu‐Ming Liu, Yu‐Chen Lin, Tsz‐Fai Leung, Ching‐Ching Yu, Wei‐Yu Lin   +6 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Efficacy of Praziquantel for Treatment of Plasmodium falciparum Infection in Asymptomatic Gabonese Adults: A Double-Blind Placebo-Controlled Randomized Trial. [PDF]

J Infect Dis
Mischlinger J, Pechmann K, Werner J, Zinsou AH, Vogler M, Ndoumba WN, Okwu DG, von Wedel C, Kurth F, Kreidenweiss A, Bachmann A, Adegnika AA, Zoleko-Manego R, Kremsner PG, Sarpong F, Badjina L, Ramharter M, Mombo-Ngoma G.   +17 more
europepmc   +1 more source