Results 61 to 70 of about 113,882 (274)

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

Chloroquine and hydroxychloroquine in the context of COVID-19

open access: yesDrugs in Context, 2020
Chloroquine and closely related structural analogs, employed initially for the treatment of malaria, are now gaining worldwide attention due to the rapidly spreading pandemic caused by severe acute respiratory syndrome-coronavirus-2, named coronavirus ...
Ashutosh M Shukla   +4 more
doaj   +1 more source

Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment [PDF]

open access: yes, 2014
During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore communities, a consistently high malaria prevalence was observed in young children despite regular treatment.
AARON ATUHAIRE   +13 more
core   +5 more sources

The Effectiveness of Local Plants from Lom and Sawang Ethnics as Antimalarial Medicine

open access: yesBiosaintifika: Journal of Biology & Biology Education, 2016
Native people or ethnic societies that live in endemic malaria islands such as in Bangka Island and Belitung Island have used many medicinal plants to cure malaria.
Henny Helmi   +2 more
doaj   +1 more source

Artemisinin displays bactericidal activity via copper-mediated DNA damage

open access: yesVirulence, 2022
Artemisinin (ARS) and its semi-synthetic derivatives are effective drugs to treat malaria and possess multiple therapeutic activities based on their endoperoxide bridge.
In-Young Chung   +6 more
doaj   +1 more source

Beyond Antimalarial Stock-outs: Implications of Health Provider Compliance on Out-of-Pocket Expenditure during Care-Seeking for Fever in South East Tanzania. [PDF]

open access: yes, 2013
To better understand how stock-outs of the first line antimalarial, Artemisinin-based Combination Therapy (ACT) and other non-compliant health worker behaviour, influence household expenditures during care-seeking for fever in the Ulanga District in ...
Abdallah, Gumi   +7 more
core   +2 more sources

First total synthesis of hoshinoamide A

open access: yesBeilstein Journal of Organic Chemistry, 2021
Hoshinoamides A, B and C, linear lipopeptides, were isolated from the marine cyanobacterium Caldora penicillata, with potent antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum.
Haipin Zhou   +5 more
doaj   +1 more source

Potential Antimalarial Activity of Artemether/Lumefantrine/Doxycycline: A Study in Mice Infected with Plasmodium berghei

open access: yesBiology, Medicine & Natural Product Chemistry, 2022
Antimalarial drug resistance is one of the greatest challenges towards eradicating malaria. Exploring new combination therapies can overcome resistance challenges.
Udeme Owunari Georgewill, Elias Adikwu
doaj   +1 more source

Nationwide Temporal Trends in Adverse Pregnancy Outcomes and Treatments in Systemic Lupus Erythematosus Pregnancy Over Two Decades in Sweden

open access: yesArthritis &Rheumatology, EarlyView.
Objective This nationwide descriptive study examined temporal trends in adverse pregnancy outcomes (APOs) and treatments in systemic lupus erythematosus (SLE) pregnancies in Sweden over 2003 to 2022. Methods Using nationwide Swedish registers, we identified 1,417 pregnancies of women with prevalent SLE and delivery dates in 2003 to 2022 and matched ...
Ngoc V. Nguyen   +6 more
wiley   +1 more source

Biological Activities of Extracts from Sumac (Rhus spp.): A Review [PDF]

open access: yes, 2007
Sumac is the common name for a genus (Rhus) that contains over 250 individual species of flowering plants in the family Anacardiaceae. These plants are found in temperate and tropical regions worldwide, often grow in areas of marginal agricultural ...
Giuseppe Mazza, Sierra Rayne
core   +2 more sources

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