Results 171 to 180 of about 54,267 (309)

Antimalarial drug discovery – the path towards eradication [PDF]

, 2013
Jeremy N. Burrows, Emilie Burlot, Brice Campo, Stéphanie Cherbuin, Sarah Jeanneret, Didier Leroy, Thomas Spangenberg, David Waterson, Timothy N. C. Wells, Paul Willis   +9 more
openalex   +1 more source

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

From methylene blue to chloroquine: a brief review of the development of an antimalarial therapy

, 2012
Kristine Krafts, Ernst Hempelmann, Agnieszka Skórska-Stania   +2 more
openalex   +2 more sources

Dual Anticancer and Antimalarial Metallodrugs: Structural Characterization, Potency Factors, ROS-Inductive and Proteasome Inhibitory Properties of Copper(II) Complexes

, 2021
Jing Wei Lai, Cheang Wei Chan, Pei Ying Ng, Mohd Jamil Maah, Rozie Sarip, Yvonne Ai Lian Lim, Loke Tim Khaw, Chew Hee Ng   +7 more
openalex   +1 more source

Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double‐Blinded, Controlled ‘Split Body’ Clinical Trial

Veterinary Dermatology, EarlyView.
ABSTRACT Background Targeted antimicrobial therapy for canine otitis externa (OE) represents an opportunity for antimicrobial stewardship. Fosmidomycin selectively inhibits the non‐mevalonate pathway for isoprenoid biosynthesis utilised by canine‐adapted, and not human‐adapted, staphylococci.
Lindsey E. Citron, Darko Stefanovski, Youwen You, Rachel Proctor, Donna Watson, Julie Randall, Christine L. Cain   +6 more
wiley   +1 more source

Netamines O–S, Five New Tricyclic Guanidine Alkaloids from the Madagascar Sponge Biemna laboutei, and Their Antimalarial Activities

, 2015
Emmanuelle Gros, Marie‐Thérèse Martin, Jonathan Sorres, Céline Moriou, Jean Vacelet, Michel Frédérich, Maurice Aknin, Yoel Kashman, Anne Gauvin‐Bialecki, Ali Al‐Mourabit   +9 more
openalex   +2 more sources

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu, James Duffy, Arnold Donkor Forkuo, Stephen Y. Gbedema, Seham Abdelall, Muhammad Wahajuddin, Huw S. Jones, Colin W. Wright   +7 more
wiley   +1 more source

Correction: Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials. [PDF]

PLoS Pathog
Tsebriy O, Khomiak A, Miguel-Blanco C, Sparkes PC, Gioli M, Santelli M, Whitley E, Gamo FJ, Delves MJ.   +8 more
europepmc   +1 more source

<i>In vitro</i> screening of ten Combretaceae plants for antimalarial activities applying the inhibition of beta-hematin formation

, 2018
Wande M. Oluyemi, Babatunde B. Samuel
openalex   +2 more sources

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source