Results 171 to 180 of about 91,276 (376)

The private commercial sector distribution chain for antimalarial drugs in Madagascar: Findings from a rapid assessment [PDF]

open access: yes, 2012
ACTwatch is a research programme funded by the Bill and Melinda Gates Foundation that aims to provide and promote evidence and recommendations for policy makers on methods to increase availability and decrease the consumer price of quality‐assured ...
ActwatchStudyGroup   +8 more
core  

New Evidence of TLR4 and TLR9 Variants Influencing Parasitaemia and Symptoms of Plasmodium vivax Infection

open access: yesInternational Journal of Immunogenetics, EarlyView.
ABSTRACT Toll‐like receptors (TLRs) induce the production of pro‐inflammatory cytokines and regulate the immune response to Plasmodium vivax infection. Genetic variants of TLRs are associated with susceptibility and severity of malaria in different populations. This study aimed to evaluate the association between polymorphisms in TLR1, TLR4, TLR7, TLR8,
Mikaele Monik Rodrigues Inácio Silva   +8 more
wiley   +1 more source

ACTwatch 2009 Supply Chain Survey Results, DRC [PDF]

open access: yes, 2012
In the DRC, as in many low‐income countries, private commercial providers play an important role in the treatment of malaria.  To design effective interventions for improved access to accurate diagnosis and effective malaria treatment, there is a need to
Akulayi Tshinungu, L   +7 more
core  

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Health System Factors Associated With Correct use of Artemether-Lumefantrine for Management of Uncomplicated Malaria in Rural Tanzania [PDF]

open access: yes
Poor adherence to and inappropriate use of antimalarials leads to ineffective cure and promote development of drug resistance. We assessed quality of malaria case management in two areas with health and demographic surveillance systems in rural Tanzania ...
Amuri, Baraka   +7 more
core  

Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Optimal treatment for frontal fibrosing alopecia (FFA) remains contentious. An international expert panel agreed that highly/ultra‐potent topical steroids were the preferred first‐line topical therapy. Preferred systemic therapies were 5‐alpha reductase inhibitors, followed by hydroxychloroquine.
Nekma Meah   +64 more
wiley   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

open access: yesJournal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao   +11 more
wiley   +1 more source

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