Results 171 to 180 of about 90,085 (338)

Influence of Citrus sinensis Seeds on the Growth Performance, Ceca Bacterial Population and the Immune System Response of Broiler Chickens

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Citrus sinensis seed powder at 0.5% in broiler diets optimized caecal bacterial populations, while 4% supplementation increased IgG levels compared to antibiotic use. These findings suggest potential benefits of orange seeds as a phytogenic feed additive, despite the need for further studies on their bioactive compounds and mechanisms.
Tchilabalo Parobali   +7 more
wiley   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

open access: yesAnnals of Human Genetics, Volume 89, Issue 5, Page 398-405, September 2025.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott   +3 more
wiley   +1 more source

Effectiveness of Antimalarial Drugs

open access: yesNew England Journal of Medicine, 2005
A global resurgence of malaria has taken place as a result of a lapse in preventive efforts and the emergence of resistance to standard antimalarial drugs. New therapies are available, but because of social, economic, and clinical factors, the use of older drugs persists.
openaire   +4 more sources

ACT Now or Later: The Economics of Malaria Resistance [PDF]

open access: yes
In the past, malaria control efforts in sub-Saharan Africa have relied on a combination of vector control and effective treatment using chloroquine. With increasing resistance to chloroquine, attention has now turned to alternative treatment strategies ...
Laxminarayan, Ramanan
core  

Characterisation of the novel quinoline RCD405: Relaxant effects on cholinergic and histaminergic tone in human bronchi and small airways

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 17, Page 4122-4133, September 2025.
Abstract Background and Purpose Increased contractility of human airway smooth muscle (hASM) is a hallmark of asthma and chronic obstructive pulmonary disease (COPD). Developing new classes of bronchodilators has proved to be challenging because of efficacy and safety concerns.
Paola Rogliani   +4 more
wiley   +1 more source

Halofantrine [PDF]

open access: yes, 1993
Bock, H. L.   +3 more
core   +1 more source

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