Results 211 to 220 of about 26,961 (258)
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Journal of the American Academy of Dermatology, 1981
The antimalarials, chloroquine, hydroxychloroquine, and quinacrine, are used primarily for malaria; but they can be beneficial for cutaneous lupus erythematosus (LE), polymorphous light eruption, solar urticaria, and porphyria cutanea tarda. Antimalarials bind to deoxyribonucleic acid (DNA) which prevents DNA and ribonucleic acid (RNA) polymerase ...
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The antimalarials, chloroquine, hydroxychloroquine, and quinacrine, are used primarily for malaria; but they can be beneficial for cutaneous lupus erythematosus (LE), polymorphous light eruption, solar urticaria, and porphyria cutanea tarda. Antimalarials bind to deoxyribonucleic acid (DNA) which prevents DNA and ribonucleic acid (RNA) polymerase ...
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Antimalarials in rheumatic diseases
Baillière's Clinical Rheumatology, 1990The antimalarials hydroxychloroquine and chloroquine remain established and effective agents for the treatment of rheumatoid arthritis and systemic lupus erythematosus. Although the mechanisms of action remain uncertain, evidence is accumulating that the antirheumatic and immunological effects of the antimalarials are related to their massive ...
Tett, S, Cutler, D, Day, R
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Synthetic peroxides as antimalarials
Medicinal Research Reviews, 2004AbstractThe discovery of artemisinin in 1971 initiated a new era in antimalarial chemotherapy. Although the clinically useful semisynthetic artemisinin derivatives are rapid acting and potent antimalarial drugs, they have short half‐lives and must be administered over a period of 5–7 days, leading to noncompliance and recrudescence.
Yuanqing, Tang +2 more
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Drug Discovery Today, 2005
Analysis of the trends in antimalarial research depicts a slow growth in launched products since 1995. However, 2002 saw the completion, after ten years, of the malarial genome project and an upsurge in products entering active development can be seen at the end of this period.
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Analysis of the trends in antimalarial research depicts a slow growth in launched products since 1995. However, 2002 saw the completion, after ten years, of the malarial genome project and an upsurge in products entering active development can be seen at the end of this period.
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Lupus, 1996
In the city of Lima, capital of Peru, the wife of the Viceroy, at that time the Count of Cinchon fell sick... Her illness was tertian fever... The rumour of her illness... became known by the people in the city, spread to neighboring places and reached Loxa. I believe since then thirty or forty years have passed.
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In the city of Lima, capital of Peru, the wife of the Viceroy, at that time the Count of Cinchon fell sick... Her illness was tertian fever... The rumour of her illness... became known by the people in the city, spread to neighboring places and reached Loxa. I believe since then thirty or forty years have passed.
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Traditional antimalarials and the development of novel antimalarial drugs
Journal of Ethnopharmacology, 2005Malaria continues to be a major cause of mortality and morbidity especially throughout the developing world. In the last 25 years or so a number of significant advances have been made that have the potential to make a major contribution to the control of this disease.
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Diaminoquinoline antimalarials
Journal of Medicinal Chemistry, 1969N D, Heindel +5 more
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