Results 11 to 20 of about 1,453 (114)
Efficacy of Different Combination Therapies for Mania in Bipolar Disorder: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Objective To systematically evaluate the efficacy and safety of different combination therapies in the treatment of mania in bipolar disorder, and to provide evidence‐based support for individualized clinical treatment. Methods PubMed, Web of Science, Cochrane Library, CNKI, VIP, and Wanfang databases were systematically searched from ...
Yao P, Ni P, Yin L.
europepmc +2 more sources
Background Polypharmacy is common among older people and is associated with an increased mortality risk. However, little is known about whether the mortality risk is related to specific medications among older adults with polypharmacy.
Yun-Ting Huang +3 more
doaj +1 more source
The role of NMDA receptors in bipolar disorder: A systematic review
Abstract Objectives Glutamatergic transmission and N‐methyl‐D‐aspartate receptors (NMDARs) have been implicated in the pathophysiology schizophrenic spectrum and major depressive disorders. Less is known about the role of NMDARs in bipolar disorder (BD).
Francesco Weiss +6 more
wiley +1 more source
Abstract Introduction Antidepressants are commonly used “off‐label” for bipolar depression, despite concerns over the risk of potential treatment‐emergent mania (or “manic switch”). Treatment‐emergent mania is difficult to study with adequate power in clinical trials as it requires a large group of participants and long follow‐up.
Oskar Hougaard Jefsen +2 more
wiley +1 more source
Effects of memantine on mania‐like phenotypes exhibited by Drosophila Shaker mutants
Amelioration of functional and metabolic parameters in Drosophila mutant upon memantine treatment. Abstract Introduction Increased glutamate levels and electrolytic fluctuations have been observed in acutely manic patients. Despite some efficacy of the non‐competitive NMDA receptor antagonist memantine (Mem), such as antidepressant‐like and mood ...
Ignazia Mocci +11 more
wiley +1 more source
Abstract Background There remain few efficacious treatments for bipolar depression, which dominates the course of bipolar disorder (BD). Despite multiple studies reporting associations between depression and cerebral blood flow (CBF), little is known regarding CBF as a treatment target, or predictor and/or indicator of treatment response, in BD ...
William S. H. Kim +16 more
wiley +1 more source
First‐line treatments for schizophrenia and schizoaffective disorder include antipsychotics and mood stabilizers, but their use may at times be limited due to severe adverse events. This case describes a 41‐year‐old male with a history of schizoaffective disorder and polysubstance use who was admitted to an inpatient psychiatry unit for acute manic and
David S. Im +3 more
wiley +1 more source
Acute secondary mania due to amoxicillin use in a patient with family history of mood disorders
The literature about manic reactions as side effects of antimicrobial agents is restricted to a limited number of case reports. We here present a secondary mania case due to antibiotic use with a positive family history for mood disorders.
Bahadır Bakım +5 more
doaj +1 more source
A systematic review and meta‐analysis of treatments for rapid cycling bipolar disorder
Abstract Objectives Rapid cycling is a common and disabling phenomenon in individuals with bipolar disorders. In the absence of a recent literature examination, this systematic review and meta‐analysis aimed to synthesise the evidence of efficacy, acceptability and tolerability of treatments for individuals with rapid cycling bipolar disorder (RCBD ...
Rebecca Strawbridge +6 more
wiley +1 more source
LITHIUM, CARBAMAZEPINE AND VALPROATE IN ACUTE MANIA
Objective: Mood stabilizers are frequently used in the management of acute mania. Lithium has been used for this indication since Cade first described its effectiveness in psychotic excitation in 1949.
M. Erkan Özcan, A. Vahap Boztepe
doaj

