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The Ascendancy of Second-Generation Antipsychotics as Frontline Antimanic Agents
Journal of Clinical Psychopharmacology, 2015 Knowledge of the factors affecting the adoption of new medications can enhance mental health care and guide quality improvement and policy development. Food and Drug Administration indications for treating bipolar disorder with several second-generation antipsychotics (SGAs) in the 2000s represent an opportunity to identify factors that impact the ...
Christopher J, Miller +9 more
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Bipolar Disorders, 2010 Memantine is a selective, uncompetitive N-methyl- D-aspartate (NMDA) receptor antagonist, currently used in the treatment of Alzheimers disease. Many clinical trials have demonstrated its tolerability and safety. We have suggested that antidepressants induce mania and rapid cycling by sensitizing dopamine D2 receptors and demonstrated that the ...
Athanasios Koukopoulos +5 more
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Annals of the New York Academy of Sciences, 2003 Abstract: A growing body of data from clinical and preclinical studies suggests that the glutamatergic system may represent a novel therapeutic target for severe recurrent mood disorders. Since synapse‐specific glutamate receptor expression/localization is known to play critical roles in synaptic plasticity, we investigated the effects of mood ...
Jing, Du +5 more
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Bipolar Disorders, 2016 ObjectivesNumerous antimanic treatments have been introduced over the past two decades, particularly second‐generation antipsychotics (SGAs). However, it is not clear whether such newer agents provide any advantage over older treatments.MethodsA historical cohort design investigated the nationwide population of outpatients with bipolar disorder treated
Mark S, Bauer +4 more
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The Journal of clinical psychiatry, 1996 This retrospective study was conducted to evaluate the relationship between the mood-stabilizing agents lithium, carbamazepine, and divalproex sodium and time course of drug response as measured by length of hospital stay.Seventy-eight patients were evaluated.
M A, Frye +4 more
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Stimulants, antidepressants, antimanics, anticonvulsants, and psychotomimetic agents
, 2001 Bev-Lorraine True, Robert H. Dreisbach
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Antimanic agents : a pharmacoepidemiologic study
Neurologia Croatica. Supplement, 1997In the treatment of bipolar affective disorders many agents have been used. An epidemiologic descriptive analysis of the drug treatment in patients with bipolar affective disorders often includes lithium, carbamazepine or valproate. These agents have shown to be effective in the acute or maintenance treatment of mania in numerous clinical trials and ...
Makarić, Gordan +3 more
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