Results 61 to 70 of about 6,234 (145)

Purine analogue 6-methylmercaptopurine ribose inhibits early and late phases of the angiogenic process.

, 1999
Angiogenesis has been identified as an important target for antineoplastic therapy. The use of purine analogue antimetabolites in combination chemotherapy of solid tumors has been proposed.
Morbidelli, L., Rusnati, M., Ribatti, D., Belleri, M., Ziche, M., Presta, M.   +5 more
core  

Efeitos do metotrexate subaracnoideo sobre a medula espinal e as meninges de coelhos

, 2014
Background: Cancer is a disease characterized by deviation of control mechanisms that regulate the survival, proliferation and differentiation of cells. Surgery, chemotherapy and radiotherapy are treatments used in oncology patients.
Lemos, Marília Freitas de
core   +1 more source

New Insights into Molecular Mechanisms of Fludarabine

, 2008
Nucleotide analogs (e.g. fludarabine) are antimetabolites used in the treatment of a wide variety of hematological malignancies and solid tumors. Upon being metabolized to their active triphosphate form, these agents are incorporated into DNA.
Bulgar, Alina D.
core  

Synthesis and Characterisation of Novel 3-Chloropiperidine Derivatives as DNA Alkylating Agents

With the advent of the 21st century, an epidemiological transition occurs in most developed nations, in which infectious diseases are gradually superseded by noncommunicable diseases such as cardiovascular disease and the neoplastic diseases.
Kirchner, Michael
core   +1 more source

Evaluation of early acute organ toxicity, biochemical and metabolic changes in pediatric oncology patients

, 2017
Kanser tüm dünyada yaygın bir sağlık problemidir ve her yıl 160,000’den fazla çocuk kanser tanısı almaktadır. Çocukluk çağı kanserlerinde kemoterapi ajanlarının kullanımı sonrası prognoz dramatik olarak artış göstermiştir.
Türkmen, Hasan
core   +1 more source

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene. [PDF]

Oncol Rep
Wang X, Chen E, Yang X, Wang Y, Quan Z, Wu X, Luo C.   +6 more
europepmc   +1 more source

Usage of hyperthermia in oncology

, 2009
Hyperthermia may be defined as a way of controlled elevation of temperature, targeted on neoplasm or adjacent tissues, organs, body part(s) or entire body.
Timorek-Lemieszczuk, Agnieszka, Nalewczyńska, Agnieszka, Śpiewankiwicz, Beata   +2 more
core  

Pharmacovigilance Analysis of Drug-Induced Stomatitis: Insights From Twenty-One Years of Real-World Data. [PDF]

Int Dent J
Liu Z, Peng L, Wang S, Liu Z, Hu L, Wang H, Yu M, Zhou Y.   +7 more
europepmc   +1 more source

Drug-induced neutropenia: A comprehensive pharmacovigilance study of the FAERS database. [PDF]

Medicine (Baltimore)
Li J, Wang Y, Gao L, Jia J, Liu J, Jiang Z.   +5 more
europepmc   +1 more source

Exploratory analysis of gene aberrations and chemotherapy response: findings from a real-world database in Japan. [PDF]

Br J Cancer
Ishibashi N, Kamatani T, Aoyama S, Tokunaga M, Kinugasa Y, Ikeda S.   +5 more
europepmc   +1 more source