Results 41 to 50 of about 6,234 (145)

Therapy-related hematologic neoplasias after breast cancer. Epidemiologic, etiologic and cytogenetic aspects and new risk factors according to published data and own results

, 2004
Background: Breast cancer is the most frequent solid tumor in women. The incidence is increasing. In Germany, about 45,000 women are newly diagnosed each year. The general strategy aims for the best local control of the tumor by surgery and radiotherapy.
Haase, Detlef, Hanf, Volker, Schulz, T.
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Cytotoxic drugs in drinking water: a prediction and risk assessment exercise for the Thames catchment in the United Kingdom

, 2009
Cytotoxic, also known as antineoplastic, drugs remain an important weapon in the fight against cancer. This study considers the water quality implications for the Thames catchment (UK) arising from the routine discharge of these drugs after use, down ...
Williams, Richard J., Johnson, Andrew C., Rowney, Nicole C.   +2 more
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Metabolic Activation And Antineoplastic-Selective Mechanism Of Action Of Two Novel Fluoropyrimidines (hplc, High Pressure Liquid Chromatography, Tetrahydrouridine, Fluorouracil)

, 1986
The coadministration of tetrahydrouridine (H(,4)Urd) diverted the metabolism of ('3)H-5-fluoro-2'-deoxycytidine (FdCyd) in human epidermoid laryngeal carcinoma (HEp-2) cells through the deoxycytidine kinase-deoxycytidylate deaminase (dCK-dCMPD) pathway ...
Boothman, David
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RESPONSE OF SACCHAROMYCES-CEREVISIAE STRAINS TO ANTINEOPLASTIC AGENTS

, 1995
The effect of several antineoplastic agents on Saccharomyces cerevisiae strains has been investigated. Minimum inhibitory concentration (MIC), minimum cytotoxic concentration (MCC) and median effective concentration (EC(50)) were determined to identify ...
DELITHEOS, A, KARAVOKYROS, I, TILIGADA, E   +2 more
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Protective Effect of Silver Nanoparticles Against Cytosine Arabinoside Genotoxicity: An In Vivo Micronucleus Assay

Cancer treatments have harmful side effects, including genotoxic ones. Our previous research discovered that a specific silver nanoparticle (AgNPs) formulation could reduce the genotoxic effects of an alkylating agent, cyclophosphamide.
Alexey Pestryakov, Balam Ruiz-Ruiz, Juan Carlos García-Ramos, Olivia Torres-Bugarín, Idalia Yazmin Castañeda-Yslas, Yanis Toledano-Magaña, María Evarista Arellano-García, Nina Bogdanchikova   +7 more
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Determination of the mechanism of action of anticancer drugs by means of the computer-assisted microscope image analysis of Feulgen-stained nuclei.

, 1997
The antitumoral effects of 30 drugs was monitored in vitro on three neoplastic cell lines. These 30 drugs belonged to various pharmacological classes which included alkylating agents, antimetabolites, Vinca alkaloids, topoisomerase II inhibitors, and ...
Atassi, Ghanem, Jean-Lambert Pasteels, Pauwels, Olivier, Kiss, Robert, Pasteels, Jean Lambert, Olivier Pauwels, Robert Kiss, Ghanem Atassi   +7 more
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Intraoperative radiation therapy in integrated treatment of rectal cancers. Results of phase II study

, 1996
Risk of local recurrence of rectal cancer remains high despite extensive therapeutic strategies, many of which have been tried to achieve better local control (i.e., external beam radiation therapy (EBRT)).
Bellantone, Rocco Domenico Alfonso, Ratto, Carlo, Cellini, Numa, Valentini, Viola, Bossola, Maurizio, Trodella, Lucio, Sofo, Luigi   +6 more
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Radiation Recall with Anticancer Agents

, 2010
Radiation recall is an acute inflammatory reaction confined to previously irradiated areas that can be triggered when chemotherapy agents are administered after radiotherapy.
Jane Hurtig, Howard A. Burris
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Precision cardio-oncology: understanding the cardiotoxicity of cancer therapy

, 2017
Current oncologic treatments have brought a strong reduction in mortality in cancer patients. However, the cancer therapy-related cardiovascular complications, in particular chemo-therapy and radiation therapy-induced cardiotoxicities are a major cause ...
Xinqiang Han, Zhou, Yun, Yun Zhou, Liu, Wendi, Wendi Liu, Han, Xinqiang   +5 more
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Analogs of alkyllysophospholipids: chemistry, effects on the molecular level and their consequences for normal and malignant cells

, 1995
In the search for new approaches to cancer therapy, the first alkyllysophospholipid (ALP) analogs were designed and studied about two decades ago, either as potential immunomodulators or as antimetabolites of phospholipid metabolism.
Vollgraf, C., Brachwitz, H.
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