Results 41 to 50 of about 7,577 (154)
Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.ABSTRACT This study aimed to evaluate the role of isoquercitrin (ISO) in 5‐fluorouracil‐induced intestinal mucositis. The animals (6 animals/group) were divided into: vehicle (2% DMSO), 5‐fluorouracil (5‐FU) and groups receiving ISO (10, 50, or 100 mg/kg).
Lázaro de Sousa Fideles +8 more
wiley +1 more source
Phytotherapy Research, Volume 40, Issue 4, Page 2003-2024, April 2026.Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam +14 more
wiley +1 more source
A simple and robust method for connecting small-molecule drugs using gene-expression signatures [PDF]
, 2008 BackgroundInteraction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with ...
Shu-Dong Zhang +20 more
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Managing Pharmacotherapy in People Living With HIV and Concomitant Malignancy. [PDF]
, 2019 Objective: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of ...
Chan, Alexandre +3 more
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Gold–Thiopurine and Thioguanine Platforms for Chemotherapy and Photodynamic Therapy
ChemistryEurope, Volume 4, Issue 3, March 2026.Gold(I)–thiopurine complexes bearing chromophores and phosphine or N‐heterocyclic carbene ligands were developed as multimodal chemo‐photodynamic agents. They show good stability, moderate lipophilicity, and tunable photoresponse. 6‐TG enhances dark cytotoxicity, 6‐MP improves phototoxicity, and PPh3/NBD provide the most efficient photoactivation ...
Laura Agulló +3 more
wiley +1 more source
UA94/6/15 Student / Alumni Personal Papers WKU Dorris Hutchinson [PDF]
, 2015 Correspondence and publications created by and about the Dorris Hutchison during her time at Sloan-Kettering ...
WKU Archives
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Journal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto +6 more
wiley +1 more source
Studies of overcoming acquired resistance : molecular mechanisms and development of novel drugs [PDF]
, 2014 Chemotherapeutic agents have become widely applied for treatment of various types of malignancies. Drug resistance unfortunately remains as a major obstacle for the effectiveness of chemotherapy.
Wang, Xin
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Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Effect of cisplatin in Mytilus galloprovincialis and of cyclophosphamide, tamoxifen and cisplatin on Ca2+ATPase [PDF]
, 2015 Relatório de Estágio de Licenciatura, Biologia Marinha, Faculdade de Ciências e Tecnologias da Universidade do Algarve, 2015In the last decade anti-cancer drugs, such as cisplatin, tamoxifen and cyclophosphamide, have seen their use greatly increase ...
Morais, Matilde
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