Results 31 to 40 of about 7,577 (154)

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma, Hirotaka Tomiyasu, Mari Takamiya, Yuko Goto‐Koshino, Atsushi Tsukamoto, Makoto Bonkobara, Masaru Okuda   +6 more
wiley   +1 more source

Antioxidant supplementation in cancer: Potential interactions with conventional chemotherapy and radiation therapy [PDF]

, 2001
Several issues are addressed in this discussion of the advantages and disadvantages of supplemental anti-oxidants during cancer treatment with chemotherapy and/or radiation ...
Staff, Clinic
core   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, Volume 159, Issue 2, Page 460-466, 15 July 2026.
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Subsequent pregnancies after a diagnosis of pregnancy‐associated cancer

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 1096-1103, June 2026.
Approximately 1 in 15 women diagnosed with pregnancy‐associated cancer went on to have a subsequent pregnancy, with markedly higher probabilities in those diagnosed before the age of 35 and those who did not undergo antineoplastic treatments. Abstract Introduction Pregnancy‐associated cancer is a rare but clinically significant event.
Giovanna Esposito, Fedro Alessandro Peccatori, Matteo Franchi, Giuseppe Trojano, Giovanni Corrao, Carlo La Vecchia, Fabio Parazzini, Anna Cantarutti   +7 more
wiley   +1 more source

The Association Between Nonalcoholic Fatty Liver Disease and Metabolic Abnormalities in The United States Population [PDF]

, 2017
BACKGROUND: Prevalence of nonalcoholic fatty liver disease (NAFLD) and rate of advanced fibrosis among individuals with metabolic syndrome (MetS) and its individual metabolic abnormalities needs better understanding in the United States population. We
Antaki, Fadi, Jinjuvadia, Raxitkumar, Liangpunsakul, Suthat, Lohia, Prateek   +3 more
core   +1 more source

Periocular Pigmentation After Gemcitabine Monotherapy for Bladder Cancer: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A patient with advanced bladder cancer received antitumor therapy consisting of gemcitabine on days 1 and 8 combined with cisplatin and treliprimab on day 1. Severe periorbital hyperpigmentation occurred 30 min after gemcitabine infusion on day 8. Symmetrical diffuse hyperpigmentation of a dark brown hue with indistinct borders appeared around
Li Juan, Chen Weiping
wiley   +1 more source

Oral considerations in pediatric patients with acute lymphoblastic leukemia [PDF]

, 2017
Introduction: Acute lymphocytic leukemia is one of the most common type of cancer in children and it is characterized by excessive and disordered immature leukocytes in the bone marrow.
Aroso, Ricardo
core  

Improving therapeutic ratio In head and neck cancer with adjuvant and cisplatin-based treatments [PDF]

, 2013
Advanced head and neck cancers are difficult to manage despite the large treatment arsenal currently available. The multidisciplinary effort to increase disease-free survival and diminish normal tissue toxicity was rewarded with better locoregional ...
Marcu, L.
core   +3 more sources

In Vitro Antimicrobial Activity and In Vivo Intestinal Barrier Regulation by Commiphora leptophloeos Bark Extract in 5‐Fluorouracil–Induced Mucositis

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT This study evaluated the phytochemical composition, antimicrobial activity, and in vivo protective effects of the hydroethanolic extract from Commiphora leptophloeos stem bark (HECL) against 5‐fluorouracil (5‐FU)‐induced intestinal mucositis. Despite the extensive traditional use of C.
Stphannie Jamyla de Araújo Barbosa, Renato Dantas‐Medeiros, Susana Barbosa Ribeiro, Amanda Silveira da Silva, Lucas Vinicius Souza de Carvalho, Rafaela Torres Dantas da Silva, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Júnior, Nizyara Costa da Silva, Raphael Victor Silva Andrade, Gabrielle Marques de Paiva, Silvana Maria Zucolotto, Rafaela Alcindo Silva de Sousa Fé, Maria Laura de Souza Lima, Raphaël Grougnet, Sergio Ortiz, Ana Caroline Zanatta, Aurigena Antunes de Araújo   +17 more
wiley   +1 more source

Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects [PDF]

, 2013
Mesenchymal stem cells (MSCs) are able to infiltrate tumor tissues and thereby effectively deliver gene therapeutic payloads. Here, we engineered murine MSCs (mMSCs) to express a secreted form of the TNF-related apoptosis-inducing ligand (TRAIL), which ...
A Ashkenazi, A Ashkenazi, A Chuntharapai, A Mohr, A Mohr, A Mohr, A Mohr, A Nakamizo, A Peister, AM van der Sloot, B Hall, C Buneker, CR Reis, D Sampath, D Stadel, DR Camidge, EW Duiker, FP Barry, GS Wu, GS Wu, I Nicoletti, J Lemke, J Luetzkendorf, JW Schymkowitz, K Ichikawa, K Papenfuss, L Zhang, LG Menon, LS Sasportas, M MacFarlane, M Vogler, M Vogler, M Vogler, ME Davis, MH Kim, MR Loebinger, MR Sprick, RM Zwacka, RW Johnstone, SB Bratton, SJ Braeuer, SM Albarenque, SM Kim, T Trarbach, TK Oost, TM Ganten, TS Griffith   +46 more
core   +1 more source