Results 1 to 10 of about 15,247 (179)
Molecules, 2023 Antimetabolites, especially 5-fluorouracil, are commonly used clinically to treat breast, colon, and other cancers. However, their side effects and inefficiency in monotherapy have prompted further searches for new combinations.
Małgorzata Milczarek +7 more
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Non-coding RNA Research, 2018 Gemcitabine and pemetrexed are clinically approved antimetabolites for the therapy of mesothelioma diseases. These drugs are often applied in combination with platinum complexes and other drugs.
Bernhard Biersack
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Biomedical Papers, 2022 By December 2019, humanity was challenged by a new infectious respiratory disease named coronavirus disease of 2019 or COVID-19. This is a viral infection based on the presence of the previously non-problematic coronavirus with assigned number 2.
Faiha M. Al-Ardhi +3 more
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Oftalʹmologiâ, 2017 The article describes modern approaches to controlling wound healing after fistulizing glaucoma surgery. It provides a classification of refractory glaucoma degrees and summarizes risk factors for excessive scarring. Author describes various applications
S. Yu. Petrov
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Molecular Systems Biology, 2014 Genome‐scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype–phenotype relationship in a mechanistic manner.
Rasmus Agren +5 more
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Cancer Metabolism and Drug Resistance
Metabolites, 2015 Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be associated with the etiology of cancer. Furthermore, accumulating evidence suggest that cancer metabolism is intimately linked to drug resistance, which is ...
Mahbuba Rahman, Mohammad Rubayet Hasan
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Variation of Cost among Anti-cancer Drugs Available in Indian Market [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Although cancer remains a major health problem all over the world, its treatment is limited by affordability of patients in a developing country like India.
Bhanu Prakash Kolasani +2 more
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New Steroidal Selenides as Proapoptotic Factors
Molecules, 2023 Cytostatic and pro-apoptotic effects of selenium steroid derivatives against HeLa cells were determined. The highest cytostatic activity was shown by derivative 4 (GI50 25.0 µM, almost complete growth inhibition after three days of culture, and over 97 ...
Izabella Jastrzebska +7 more
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Xeloda as first-line therapy of metastatic colorectal cancer-our experience [PDF]
Archive of Oncology, 2002 BACKGROUND: Results of phase III clinical studies comparing efficacy of Xeloda vs. standard 5-FU/FA protocols as first line therapy of metastatic colorectal carcinoma (MCRC), have shown better efficacy of Xeloda, with less toxic adverse effects, apart ...
Kovčin Vladimir +4 more
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Frontiers in Immunology, 2020 Cationic antimicrobial peptides (AMPs) are active immune effectors of multicellular organisms and are also considered as new antimicrobial drug candidates.
Alexandro Rodríguez-Rojas +8 more
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