Results 31 to 40 of about 15,247 (179)

Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis

open access: yesTürk Oftalmoloji Dergisi, 2016
Pediatric uveitis may be a serious health problem because of the lifetime burden of vision loss due to severe complications if the problem is not adequately treated.
İlknur Tuğal-Tutkun
doaj   +1 more source

Control of Gemcitabine Activity With Blue and Red Light

open access: yesChemistry – A European Journal, EarlyView.
Treating cancer with chemotherapy is generally associated with many side effects, which can be addressed by selectively releasing the desired drugs with visible light. Sixteen new blue light‐activatable cytostatics were introduced, with the gemcitabine derivative exhibiting ideal properties.
Nils F. Kersten   +6 more
wiley   +1 more source

MODERN ONCO DRUG FOR INTERNAL USE

open access: yesФармация и фармакология (Пятигорск), 2018
Despite the development of biotherapy, chemotherapy remains one of the main methods of treatment of cancer patients. Currently, there are more than 100 anticancer drug substances, however, every year new drugs enter clinical practice and various ...
O. L. Orlova   +7 more
doaj   +1 more source

Role of Rutin in 5-Fluorouracil-Induced Intestinal Mucositis: Prevention of Histological Damage and Reduction of Inflammation and Oxidative Stress

open access: yesMolecules, 2020
Intestinal mucositis, characterized by inflammatory and/or ulcerative processes in the gastrointestinal tract, occurs due to cellular and tissue damage following treatment with 5-fluorouracil (5-FU).
Lázaro de Sousa Fideles   +19 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit   +7 more
wiley   +1 more source

Prevention of corneal complications after post-operative application of antimetabolites following non-penetrating deep sclerectomy

open access: yesОфтальмохирургия
Purpose. To evaluate the clinical and functional effectiveness of the developed method for prevention of corneal complications of non-penetrating deep sclerectomy (NPDS) with postoperative adjuvant use of 5-fluorouracil in comparison with the control ...
S.N. Svetozarskii   +3 more
doaj   +1 more source

The investigation of antinutritional factors in Phaseolus vulgaris. Environmental and varietal differences [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 1999
This study enables us to indicate that the oligosaccharide raffinose family, phytate, saponin and lectin contents of P. vulgaris are clearly influenced by both environmental and genetics factors.
Burbano C.   +4 more
doaj  

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

The first investigation on differences in the effectiveness of mycophenolate mofetil and azathioprine antimetabolites determined in Polish patients treated for non-infectious uveitis

open access: yesAnnals of Agricultural and Environmental Medicine, 2020
Introduction The non-infectious uveitis, a serious vision-threatening disease is the fourth most common cause of blindness in working population of the developed world.
Maja Waszczyk-Łączak   +5 more
doaj   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

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