Results 1 to 10 of about 6,213 (108)

Trends in antineoplastic drug use, cost and prescribing patterns among patients with lung cancer in nine major cities of China, 2016–2020: a retrospective observational study based on inpatient and outpatient hospital data

BMJ Open, 2023
Objectives It is unclear whether the use of antineoplastic drugs for patients with lung cancer in China has changed after the implementation of the national drug price negotiation in 2016 and continual update of clinical guidelines.
Yi Liu, Lixin Zhou, Xiaohong Zhang, Feng Yang, Rongrong Fan, Jingyuan Shang, Lin Huang, Yanguo Liu, Chunyan Zhang, Li'an Zu, Yufei Feng   +10 more
doaj   +1 more source

Antineoplastics Encapsulated in Nanostructured Lipid Carriers

Molecules, 2021
Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays, with well-defined therapeutic protocols.
Gustavo Henrique Rodrigues da Silva, Ludmilla David de Moura, Fabíola Vieira de Carvalho, Gabriela Geronimo, Talita Cesarim Mendonça, Fernando Freitas de Lima, Eneida de Paula   +6 more
doaj   +1 more source

Polimorfismos genéticos asociados a toxicidad en el tratamiento con 5-fluorouracilo en pacientes con cáncer colorrectal

Oncología, 2022
Introduction: Colorectal cancer is the most common malignancy of the digestive tract. The treatment is based basically on administering antitumor medications, like 5-fluorouracil (5-FU), which belongs to the antimetabolites, antineoplastic agents ...
Cristina Benavides Tutillo, Gabriela Molina Pinos , Maritza Ochoa Castro   +2 more
doaj   +1 more source

The Role of Chemotherapy in the Treatment of Hodgkin’s Disease

Revista Brasileira de Cancerologia, 2023
Trabalho apresentado no Simpósio Internacional sobre Doença de Hodgkin, realizado no Instituto Nacional de Câncer no Rio de Janeiro — 16 a 20 de Janeiro de 1967. Transcrição da gravação, revisto o original pelo autor.
David A. Karnofsky
doaj   +1 more source

Xeloda as first-line therapy of metastatic colorectal cancer-our experience [PDF]

Archive of Oncology, 2002
BACKGROUND: Results of phase III clinical studies comparing efficacy of Xeloda vs. standard 5-FU/FA protocols as first line therapy of metastatic colorectal carcinoma (MCRC), have shown better efficacy of Xeloda, with less toxic adverse effects, apart ...
Kovčin Vladimir, Ješić Rada, Krivokapić Zoran V., Andrić Zoran, Pavlović Aleksandra   +4 more
doaj   +1 more source

Study of the use possibility of the chemical-biological adduct of the 1,1-bis-[5-bromopyrimidine-2’,4’-diono-1’-il]-2-bromo-2’-chloroethylene and bacterial lectin for the treatment of the Pliss’ lymphosarcoma

Zaporožskij Medicinskij Žurnal, 2015
Aim. Study of the pyrimidine metabolism antimetabolites that can be preformed compounds in the link of biosynthetic processes and can brake tumour’s growth is a more successful, perspective finding direction of new antitumor medications.
O. V. Welchinska
doaj   +1 more source

Efficiency of four solutions in removing 23 conventional antineoplastic drugs from contaminated surfaces.

PLoS ONE, 2020
BackgroundResidual contamination by intravenous conventional antineoplastic drugs (ICAD) is still a daily issue in hospital facilities. This study aimed to compare the efficiency (EffQ) of 4 different solutions to remove 23 widely used ICADs from ...
Nicolas Simon, Nicolas Guichard, Pascal Odou, Bertrand Decaudin, Pascal Bonnabry, Sandrine Fleury-Souverain   +5 more
doaj   +1 more source

Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations

Journal of Translational Medicine, 2009
The dose-delivery schedule of conventional chemotherapy, which determines its efficacy and toxicity, is based on the maximum tolerated dose. This strategy has lead to cure and disease control in a significant number of patients but is associated with ...
Tourkova Irina L, Shurin Galina V, Kaneno Ramon, Shurin Michael R   +3 more
doaj   +1 more source

Novel Approaches for Concurrent Irradiation in Locally Advanced Cervical Cancer: Platinum Combinations, Non-Platinum-Containing Regimens, and Molecular Targeted Agents

Obstetrics and Gynecology International, 2013
Despite the available prevention and early detection strategies, squamous-cell carcinoma of the uterine cervix is still diagnosed as locally advanced disease in a considerable proportion of patients.
Giannis Mountzios, Aspasia Soultati, Dimitrios Pectasides, Meletios A. Dimopoulos, Christos A. Papadimitriou   +4 more
doaj   +1 more source

Assay of some biologically active antimetabolite antineoplastic drugs with N-bromosuccinimide reagent

, 2005
Department of Chemistry, University of Allahabad, Allahabad-211 002, India E-mail: poonamjai92@rediffmail.com Poonam_J9672000@yahoo.com Manuscript received 8 October 2004, revised 10 August 2005. accepted 17 August 2005 In the present investigation a simple, sensitive, selective, quick and convenient method has been developed for the determination of ...
Poonam Jaiswal, P. K. Dwivedi, I. C. Shukla   +2 more
openaire   +1 more source