Results 1 to 10 of about 105,478 (251)

Therapeutic methods and effect on keloid and hypertrophic scars: a systematic review [PDF]

open access: yesFrontiers in Medicine
BackgroundKeloids and hypertrophic scars are fibroproliferative disorders with high recurrence rates, lacking a definitive treatment standard. This review systematically evaluates current therapies and their effectiveness in treating keloid and ...
Yuhang Shen   +8 more
doaj   +2 more sources

A Pilot Study of Peritumor Administration of 5-FU for Preventing Bleeding in Advanced Gastric Cancer

open access: yesThe Korean Journal of Gastroenterology, 2022
Five-FU is a potent chemotherapeutic agent for suppressing endothelial cell growth. The purpose of this study was to investigate the usefulness of local peritumor injection of 5-FU for patients with advanced gastric cancer (AGC) for the prevention of ...
Nam-Hee Kim   +4 more
doaj   +1 more source

Hypertriglyceridemia Induced by Fluorouracil: A Novel Case Report

open access: yesCase Reports in Oncology, 2021
We had previously reported on S-1-induced hypertriglyceridemia. Here, we report fluorouracil-induced hypertriglyceridemia in a patient with capecitabine-induced hypertriglyceridemia and the corresponding therapeutic process.
Yoshitaka Saito   +4 more
doaj   +1 more source

The rate of cardiac complications in patients receiving a 24-hour dose of 5-Fluorouracil [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. Cardiotoxicity caused by fluoropyrimidines is an uncommon but potentially fatal complication. Its frequency has been 1.6 to 19% in previous studies. But there are no accurate statistics in Iran. The aim of this study was to determine the rate
Mostafa Davoodnataj   +4 more
doaj   +1 more source

5FU-loaded PCL/Chitosan/Fe3O4 Core-Shell Nanofibers Structure: An Approach to Multi-Mode Anticancer System [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2022
Purpose: 5-Fluorouracil (5FU) and Fe3O4 nanoparticles were encapsulated in core-shellpolycaprolactone (PCL)/chitosan (CS) nanofibers as a multi-mode anticancer system to studydrug release sustainability.
Mehdi Hadjianfar   +4 more
doaj   +1 more source

PHYSIOLOGICAL AND BIOCHEMICAL CHANGES FOR 5- FLUOROURACIL DRUG (ANTI-CANCER) IN CANCER PATIENTS [PDF]

open access: yesBasrah Journal of Veterinary Research, 2017
The study was conducted to determine the effect of the 5-Fluorouracil (5-FU) drug is a medication used to treat cancer or the knowledge of 5-FU drug(anticancer) effect might help to attribute these side on physiological and biochemical parameters in ...
Baida R. Ali
doaj   +1 more source

The Impact of Metformin on the Development of Hypothyroidism and Cardiotoxicity Induced by Cyclophosphamide, Methotrexate, and Fluorouracil in Rats

open access: yesPharmaceuticals, 2023
Cyclophosphamide (CYP), methotrexate (MTX), and 5-fluorouracil (5-FU) are extensively utilized in the therapeutic management of various malignancies. It is noteworthy, however, that potential chemotherapy-related complications include the occurrence of ...
Ahmad H. Alhowail, Maha A. Aldubayan
doaj   +1 more source

A Bibliometric Analysis of Cyclophosphamide, Methotrexate, and Fluorouracil Breast Cancer Treatments: Implication for the Role of Inflammation in Cognitive Dysfunction

open access: yesFrontiers in Molecular Biosciences, 2021
Inflammation is considered one of the possible mechanisms behind long-term cognitive dysfunction persistent after chemotherapy treatment. The chemotherapy combination of cyclophosphamide, methotrexate, and fluorouracil (CMF) was one of the older methods ...
Christa Corley   +4 more
doaj   +1 more source

Xanthine Oxidase Inhibitor, Febuxostat Is Effective against 5-Fluorouracil-Induced Parotid Salivary Gland Injury in Rats Via Inhibition of Oxidative Stress, Inflammation and Targeting TRPC1/CHOP Signalling Pathway

open access: yesPharmaceuticals, 2022
The current research aimed to examine the ameliorative role of febuxostat (FEB), a highly potent xanthine oxidase inhibitor, against 5-fluorouracil (5-FU)-induced parotid salivary gland damage in rats, as FEB is a pleiotropic drug that has multiple ...
Walaa Yehia Abdelzaher   +5 more
doaj   +1 more source

Fluorouracil Supplemented With Oxaliplatin or Irinotecan for Solid Tumors: Indications From Clinical Characteristics and Health Outcomes of Patients

open access: yesFrontiers in Oncology, 2020
Fluorouracil combined with oxaliplatin (FOLFOX) and fluorouracil combined with irinotecan (FOLFIRI) are both first-line clinical chemotherapy regimens. However, clinicians' selection of FOLFIRI or FOLFOX medication regimens and their effects on patients'
Zhao Qingwei   +8 more
doaj   +1 more source

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