Results 11 to 20 of about 142,003 (296)

High incidence of Angina pectoris in patients treated with 5-fluorouracil - A planned surveillance study with 102 patients [PDF]

, 2003
Objective: Angina pectoris, arrhythmic sudden death and myocardial infarction, all these cardiac events have occasionally been reported during 5-fluorouracil (5-FU) chemotherapy.
Lersch, C., Wacker, A., Scherpinski, U., Reindl, L., Seyfarth, M., Wacker, Annette;Lersch, Christian;Scherpinski, Ute;Reindl, Laurence;Seyfarth, Melchior, Wacker, A;Lersch, C;Scherpinski, U;Reindl, L;Seyfarth, M   +6 more
core   +1 more source

Curcumin Chemosensitizes 5-Fluorouracil Resistant MMR-Deficient Human Colon Cancer Cells in High Density Cultures [PDF]

, 2014
Objective Treatment of colorectal cancer (CRC) remains a clinical challenge, as more than 15% of patients are resistant to 5-Fluorouracil (5-FU)-based chemotherapeutic regimens, and tumor recurrence rates can be as high as 50–60%.
Patricia Kraehe, Kraehe Patricia, Shayan, Parviz, Lueders, Cora, Shayan Parviz, Lueders Cora, Shakibaei Mehdi, Mehdi Shakibaei, Parviz Shayan, Goel Ajay, Buhrmann Constanze, Ajay Goel, Cora Lueders, Shakibaei, Mehdi, Constanze Buhrmann, Buhrmann, Constanze, Goel, Ajay, Kraehe, Patricia   +17 more
core   +1 more source

5-Fluorouracil combined with cisplatin via arterial induction for advanced T-stage nasopharyngeal carcinoma: A 10-year outcome of a phase I/II study

Frontiers in Oncology, 2022
Background and PurposeCurrently, there is no optimal dose recommendation for a 120-h continuous infusion of 5-fluorouracil via arterial cannulation for advanced T-stage nasopharyngeal carcinoma (NPC).
Li Xiang, Yun Zheng, PeiRong Ren, Sheng Lin, JianWen Zhang, QingLian Wen, LiJia He, ChangLing Shang, JingBo Wu   +8 more
doaj   +1 more source

Fluorouracil

, 2006
europepmc   +2 more sources

Effective second-line treatment with cetuximab and bevacizumab in a patient with hepatic metastases of colorectal cancer and hyperbilirubinemia [PDF]

, 2007
Background: Irinotecan-based second-line chemotherapy of metastatic colorectal cancer (CRC) is effective, it might, however, be contraindicated in cases of severe liver dysfunction due to advanced liver metastases.
Moosmann, Nicolas, Schulz, Christoph, Laessig, Dorit, Michaely, Henrik Jakob, Heinemann, Volker   +4 more
core   +1 more source

The rate of cardiac complications in patients receiving a 24-hour dose of 5-Fluorouracil [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. Cardiotoxicity caused by fluoropyrimidines is an uncommon but potentially fatal complication. Its frequency has been 1.6 to 19% in previous studies. But there are no accurate statistics in Iran. The aim of this study was to determine the rate
Mostafa Davoodnataj, Mohsen Vakili Sadeghi, Naghmeh Zieaie Amiri, Majid Nabipour, Hemmat Gholinia Ahangar   +4 more
doaj   +1 more source

THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): 5-Fluorouracil (5-FU) is currently the main drug used in chemotherapy for gastric cancer (GC). The main clinical problems of 5-FU therapy are insensitivity and acquired resistance to 5-FU.
Xianke Lin, Jiajia Pan, Hammza Hamoudi, Jiren Yu   +3 more
doaj   +1 more source

Evaluation of the Expression Profile of Irinotecan-Induced Diarrhea in Patients with Colorectal Cancer

Pharmaceuticals, 2021
Irinotecan (CPT-11) is widely used for the treatment of unresectable colorectal cancer in combination with fluoropyrimidines, such as 5-fluorouracil and S-1.
Mashiro Okunaka, Daisuke Kano, Reiko Matsui, Toshikatsu Kawasaki, Yoshihiro Uesawa   +4 more
doaj   +1 more source

5FU-loaded PCL/Chitosan/Fe3O4 Core-Shell Nanofibers Structure: An Approach to Multi-Mode Anticancer System [PDF]

Advanced Pharmaceutical Bulletin, 2022
Purpose: 5-Fluorouracil (5FU) and Fe3O4 nanoparticles were encapsulated in core-shellpolycaprolactone (PCL)/chitosan (CS) nanofibers as a multi-mode anticancer system to studydrug release sustainability.
Mehdi Hadjianfar, Dariush Semnani, Jaleh Varshosaz, Sajad Mohammadi, Sayed Pedram Rezazadeh Tehrani   +4 more
doaj   +1 more source

Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure [PDF]

, 2002
Background: The cytotoxic treatment of patients suffering from advanced or metastatic cancer undergoing hemodialysis due to chronic renal failure still remains a problem, since for those patients pharmacokinetic and pharmacodynamic data on most cytotoxic
Stemmler, J., Hacker, U., Schalhorn, A., Weise, A., Heinemann, Volker   +4 more
core   +1 more source