Results 41 to 50 of about 1,122,870 (303)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesIntroduction: Optimizing antibiotic therapy is essential given the growing antimicrobial resistance. Variability in therapeutic decision-making among health professionals is a challenge, especially across different stages of training.
Victor Hugo Ovani Marchetti +3 more
doaj +1 more source
Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2017 The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities.
Romanov A.V. +7 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
A Retrospective Data Analysis of the Structure of Isolated Microorganisms in Secondary Skin and Soft Tissue Infections Using Permuted Test [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2016 Objective. Objectives. To analyze the structure of microorganisms isolated in patients with secondary skin and soft tissues infection (SSTIs) (trophic ulcers in patients with diabetes mellitus (DM), chronic arterial insufficiency (CAI), chronic venous ...
Kuzmenkov A.Yu. +5 more
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Pharmaceuticals, 2013 The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents. Here we review the history and new development of antimicrobial peptides (AMPs), a growing class of natural and synthetic
Ali Adem Bahar, Dacheng Ren
openaire +3 more sources
, 2010 Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe +2 more
core +1 more source
Extraction Of Defensin Antimicrobial Peptide From SWISS-PROT Database Using Extended Boyer-More Algorithm. [PDF]
, 2007 Antimicrobial Peptide (AMP) is a subset of protein that plays an essential role in innate immunity system. Researches on AMP are actively conducted in Immunology field where synthetics antibiotics are being developed. There are several classifications of
Ahamed Hassain Malim, N.H. +1 more
core +1 more source
AMRmap: an online platform for monitoring antibiotic resistance [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2017 This review describes the new Internet resource AMRmap (map.antibiotic.ru), which provides data on antibiotic resistance in the Russian Federation.
Kuzmenkov A.Yu. +5 more
doaj