Results 31 to 40 of about 1,122,870 (303)

Antimicrobial resistance among commensal isolates of Escherichia coli and Staphylococcus aureus in the Indonesian population inside and outside hospitals [PDF]

, 2008
The prevalence of antimicrobial resistance among the commensal microflora was examined in the Indonesian population inside and outside hospitals. A total of 3,995 individuals were screened in two major urban centers.
Filius, P. M. G., Verbrugh, H. A., Lestari, ES, Duerink, D. O., Kuntaman, K, Kuntaman , K., Wahjono, H, Severin, Juliette, Severin , J. A, Wahjono, H., Duerink, DO, Hadi, U., Filius, PMG (Margreet), Hadi, U, Lestari , E. S., Verbrugh, Henri   +15 more
core   +2 more sources

RULE-BASED DIGITAL CLINICAL ALGORITHM VERSUS RESIDENT PHYSICIANS AND INFECTIOUS DISEASE SPECIALISTS IN ANTIBIOGRAM-GUIDED ANTIBIOTIC SELECTION: PRELIMINARY EVALUATIONS OF A CLINICAL DECISION SUPPORT SYSTEM

Brazilian Journal of Infectious Diseases
Introduction/Objective: Evaluating clinical decisions across different professional training profiles is essential to understand the limits and potential of clinical decision support systems in medical practice. This study aimed to compare the proportion
Victor Hugo Ovani Marchetti, Mariana Lanna Magalhães Veríssimo, Juliana Veríssimo Lanna, Natanael Sutikno Adiwardana   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The in Vitro Antimicrobial Activity of Fruit and Leaf Crude Extracts of Momordica Charantia: A Tanzania Medicinal Plant. [PDF]

, 2009
To evaluate the antimicrobial activity of Momordica charantia extracts on reference strains and microorganisms isolated from clinical specimens.
Mwambete, KD, Mwambete, K.D, Mwambete, K. D., Mwambete, K D   +3 more
core   +1 more source

AGREEMENT ANALYSIS BETWEEN AN ALGORITHM AND INFECTIOUS DISEASE SPECIALISTS IN ANTIBIOGRAM-GUIDED ANTIBIOTIC SELECTION

Brazilian Journal of Infectious Diseases
Introduction/Objective: Variability among specialists within the same specialty limits studies that use clinical judgment as a gold standard and can lead to inconsistent decisions.
Victor Hugo Ovani Marchetti, Mariana Lanna Magalhães Veríssimo, Juliana Veríssimo Lanna, Natanael Sutikno Adiwardana   +3 more
doaj   +1 more source

Risk factors and outcomes associated with persistent vancomycin resistant Enterococcal Bacteremia

BMC Infectious Diseases, 2022
Background Prior studies have identified that vancomycin resistant enterococcus (VRE) bacteremia that persists for four days or more is an independent predictor of mortality.
Emily Fox, David Ha, Mark Bounthavong, Lina Meng, Emily Mui, Marisa Holubar, Stanley Deresinski, William Alegria   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs [PDF]

, 2011
Antimicrobial peptides (AMPs) are naturally occurring entities with potential as pharmaceutical candidates and/or food additives. They are present in many organisms including bacteria, insects, fish and mammals.
O\u27Brien, Peter J., David J. Brayden, Baird, Alan W., Peter J. O’Brien, Marc Devocelle, Devocelle, Marc, Sam Maher, Alan W. Baird, Maher, Sam, Edwin G. Walsh, Walsh, Edwin G., O'Brien, Peter J., Brayden, David James   +12 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

COMPARISON BETWEEN A DETERMINISTIC DIGITAL ALGORITHM AND LARGE LANGUAGE MODELS FOR DECISION-MAKING ON UROCULTURE-GUIDED ANTIBIOTIC THERAPY

Brazilian Journal of Infectious Diseases
Introduction: The increasing use of artificial intelligence (AI) in clinical decision-making requires rigorous validation, especially in critical scenarios such as antimicrobial prescribing guided by antibiogram.
Victor Hugo Ovani Marchetti, Mariana Lanna Magalhães Veríssimo, Juliana Veríssimo Lanna, Natanael Sutikno Adiwardana   +3 more
doaj   +1 more source