Results 31 to 40 of about 989,932 (316)
Risk factors and outcomes associated with persistent vancomycin resistant Enterococcal Bacteremia
BMC Infectious Diseases, 2022 Background Prior studies have identified that vancomycin resistant enterococcus (VRE) bacteremia that persists for four days or more is an independent predictor of mortality.
Emily Fox +7 more
doaj +1 more source
Antimicrobial Drug Resistance in Taiwan
, 2009 Antimicrobial resistance is a major health problem worldwide , but marked variations in the resistance profiles of bacterial pathogens are found between countries and in different patient settings, especially in Asia.
HUANG, YU-TSUNG;HSUEH, PO-REN +1 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Human Chemokines as Antimicrobial Peptides with Direct Parasiticidal Effect on Leishmania mexicana In Vitro [PDF]
, 2013 Chemokines and chemokine receptor-mediated effects are important mediators of the immunological response and cure in human leishmaniasis. However, in addition to their signalling properties for leukocytes, many chemokines have also been shown to act ...
Paul Bates (134046) +18 more
core +1 more source
Brazilian Journal of Infectious DiseasesIntroduction/Objective: Evaluating clinical decisions across different professional training profiles is essential to understand the limits and potential of clinical decision support systems in medical practice. This study aimed to compare the proportion
Victor Hugo Ovani Marchetti +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesIntroduction/Objective: Variability among specialists within the same specialty limits studies that use clinical judgment as a gold standard and can lead to inconsistent decisions.
Victor Hugo Ovani Marchetti +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Brazilian Journal of Infectious DiseasesIntroduction: The increasing use of artificial intelligence (AI) in clinical decision-making requires rigorous validation, especially in critical scenarios such as antimicrobial prescribing guided by antibiogram.
Victor Hugo Ovani Marchetti +3 more
doaj +1 more source
Antimicrobial polypeptides [PDF]
Journal of Leukocyte Biology, 2003 AbstractThe respiratory tract presents a large and potentially vulnerable surface to inhaled microbes. It is coated by a thin layer of secretions generated by airway epithelial cells, submucosal glands, resident and recruited phagocytes (neutrophils, eosinophils, monocytes, and macrophages) and alveolar epithelial cells, as well as substances that ...
openaire +2 more sources