Importance of antimicrobial stewardship in solid organ transplant recipients: An ESCMID perspective. [PDF]
BackgroundIn the last decades, solid organ transplantation (SOT) has emerged as an important method in the management of chronic kidney, liver, heart, and lung failure.
Supported by the ESCMID Study Group for Antimicrobial Stewardshi +22 more
core +1 more source
Antimicrobial drug use and resistance in Europe [PDF]
Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that ...
Grundmann, Hajo +8 more
core +3 more sources
Legal framework of antimicrobial stewardship in hospitals (LEASH) : a European Society of Clinical Microbiology and Infectious Diseases (ESCMID) cross-sectional international survey [PDF]
Antimicrobial stewardship (AMS) is the cornerstone activity in the combat against antimicrobial resistance. In order to ensure sustainable deployment and development of AMS, a strategic and regulatory framework needs to be provided by national healthcare
Béraud, Guillaume +17 more
core +1 more source
Antimicrobial resistance is a global health concern; Enterobacterales resistant to third-generation cephalosporins (3GCs) and carbapenems are of the highest priority.
Shizuo Kayama +14 more
doaj +1 more source
We are living in a time of enormous risk. Years of antibiotic overuse and misuse has contributed to a global threat, where an increase in antibiotic resistant bacteria are contributing to approximately 700,000 deaths per year. International institutions such as the World Health Organization (WHO) and the UK government are calling for new antibiotics ...
Birnbaum, H, Roughley, M, D'Sa, R
openaire +2 more sources
Population structure of Pseudomonas aeruginosa in the Russian Federation: role of high-risk clones in spread of carbapenemases and carbapenem resistance [PDF]
Objective. To determine the population structure of clinical P. aeruginosa isolates recovered from hospitals in different regions of Russia and to assess the role of high-risk clones in the dissemination of carbapenemases and carbapenem resistance ...
Edelstein M.V. +10 more
doaj +1 more source
Antimicrobial Therapy and Antimicrobial Stewardship in Sepsis
Since sepsis was first defined, sepsis management has remained challenging. To improve mortality rates for sepsis and septic shock, an accurate diagnosis and prompt administration of appropriate antibiotics are essential. The goals of antimicrobial stewardship are to achieve optimal clinical outcomes and to ensure cost-effectiveness and minimal ...
Hyeri Seok, Ji Hoon Jeon, Dae Won Park
openaire +2 more sources
Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Francisco J. L. Aragão (132479) +31 more
core +1 more source
Pneumococcal vaccination in adult patients with comorbidities: a review of the clinical practice guidelines [PDF]
The review discusses national clinical practice guidelines for pneumococcal vaccination in different countries, existing approaches to adult immunization, and highlights key results of the most significant clinical studies and metaanalyses on the ...
Kozlov R.S. +3 more
doaj +1 more source
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all multicellular organisms. These proteins can have broad activity to directly kill bacteria, yeasts, fungi, viruses and even cancer cells.
Zhang, Ling-juan, Gallo, Richard L.
openaire +2 more sources

