Results 71 to 80 of about 1,122,870 (303)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Limited effect of patient and disease characteristics on compliance with hospital antimicrobial guidelines [PDF]

, 2005
Objective: Physicians frequently deviate from guidelines that promote prudent use of antimicrobials. We explored to what extent patient and disease characteristics were associated with compliance with guideline recommendations for three common infections.
Gans, ROB; id_orcid, Mol, PGM; id_orcid, Wieringa, Jaap E., Denig, P., Laseur, M., Haaijer-Ruskamp, F.M., Mol, Peter G. M.; id_orcid, Mol, PGM, Degener, JE, NannanPanday, P.V., Laseur, M, Denig, P; id_orcid, Wieringa, J.E., Haaijer-Ruskamp, Flora M., Mol, Peter G. M., Denig, P, NannanPanday, PV, Gans, ROB, Degener, John E., Mol, P.G.M., Gans, Rijk O. B., Gans, Rijk O. B.; id_orcid, Gans, R.O.B., Haaijer-Ruskamp, FM, Degener, J.E.   +24 more
core   +2 more sources

Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2015
Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods.
Kozlov R.S., Golub A.V., Dekhnich A.V., Sukhorukova M.V., SMART Study Group   +4 more
doaj  

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Adherence barriers to antimicrobial treatment guidelines in teaching hospital, the Netherlands [PDF]

, 2004
To optimize appropriate antimicrobial use in a university hospital and identify barriers hampering implementation strategies, physicians were interviewed regarding their opinions on antimicrobial policies.
Gans, ROB; id_orcid, Gans, ROB, Mol, PGM; id_orcid, Rijk O.B. Gans, Haaijer-Ruskamp, F.M., Flora M. Haaijer-Ruskamp, Rutten, WJMJ, Mol, P.G.M., John E. Degener, Mol, PGM, Peter G.M. Mol, Degener, JE, Gans, R.O.B., Haaijer-Ruskamp, FM, Willem J.M.J. Rutten, Degener, J.E., Rutten, W.J.M.J.   +16 more
core   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Bacterial Resistance to Antimicrobial Agents

, 2021
Bacterial pathogens as causative agents of infection constitute an alarming concern in the public health sector. In particular, bacteria with resistance to multiple antimicrobial agents can confound chemotherapeutic efficacy towards infectious diseases ...
Nicholas Wenzel, Sanath H. Kumar, Manisha Ojha, Jerusha Stephen, Alberto J. Hernandez, Leslie M. Sanford, Manjusha Lekshmi, Ammini Parvathi, Manuel F. Varela   +8 more
core   +1 more source

Antimicrobial polypeptides [PDF]

Journal of Leukocyte Biology, 2003
AbstractThe respiratory tract presents a large and potentially vulnerable surface to inhaled microbes. It is coated by a thin layer of secretions generated by airway epithelial cells, submucosal glands, resident and recruited phagocytes (neutrophils, eosinophils, monocytes, and macrophages) and alveolar epithelial cells, as well as substances that ...
openaire   +2 more sources

Antimicrobial Resistance Predicts Death in Tanzanian Children with Bloodstream Infections: A Prospective Cohort Study. [PDF]

, 2007
Bloodstream infection is a common cause of hospitalization, morbidity and death in children. The impact of antimicrobial resistance and HIV infection on outcome is not firmly established.
Roland Jureen, Langeland, Nina, Maselle, Samwel Y, Karim P Manji, Samwel Y Maselle, Mwakagile, Davis S. M., Jureen, R., Msangi, V., Bjørn Blomberg, Viola Msangi, Tamim, Bushir S, Manji, Karim P, Holberg-Petersen, Mona, Maselle, Samwel Y., Davis SM Mwakagile, Langeland, N., Mona Holberg-Petersen, Marit G Tellevik, Nina Langeland, Msangi, Viola, Jureen Roland, Jureen, Roland, Harthug, Stig, Blomberg, B., Urassa, Willy K, Urassa, Willy K., Harthug, S., Bushir S Tamim, Tamim Bushir S, Maselle, S.Y, Urassa, W.K, Tamim, Bushir S., Msangi Viola, Harthug Stig, Langeland Nina, Mwakagile Davis SM, Tellevik, M.G, Mwakagile, D.S.M, Maselle Samwel Y, Tellevik, Marit G, Manji, Karim P., Tamim, B.S, Manji, K.P, Holberg-Petersen, M., Urassa Willy K, Willy K Urassa, Manji Karim P, Holberg-Petersen Mona, Blomberg, Bjørn, Mwakagile, Davis S M, Stig Harthug, Tellevik Marit G, Blomberg Bjørn, Tellevik, Marit Gjerde   +53 more
core   +2 more sources

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source