Results 71 to 80 of about 989,932 (316)

A validation study on a standardized assessment algorithm for antimicrobial prescribing appropriateness

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Since 2013, the Australian Hospital National Antimicrobial Prescribing Survey (Hospital NAPS) has provided a standardized framework for hospitals to assess the quality of antimicrobial prescribing.
Caroline Chen   +7 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs

open access: yes, 2011
Antimicrobial peptides (AMPs) are naturally occurring entities with potential as pharmaceutical candidates and/or food additives. They are present in many organisms including bacteria, insects, fish and mammals.
O\u27Brien, Peter J.   +12 more
core   +1 more source

Small molecule produced by Photorhabdus interferes with ubiquinone biosynthesis in Gram-negative bacteria

open access: yesmBio
We report the identification of 3,6-dihydroxy-1,2-benzisoxazole (DHB) in a screen of Photorhabdus and Xenorhabdus, whose symbiotic relationship with eukaryotic nematodes favors secondary metabolites that meet several requirements matching those for ...
Rachel Bargabos   +9 more
doaj   +1 more source

In vivo evolution of an emerging zoonotic bacterial pathogen in an immunocompromised human host

open access: yesNature Communications, 2021
Bordetella hinzii is an emerging pathogen with zoonotic risk to humans, known to be able to cause respiratory tract infection, bacteremia and endocarditis.
A. Launay   +5 more
doaj   +1 more source

Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2015
Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods.
Kozlov R.S.   +4 more
doaj  

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study from the EUSTAR Cohort

open access: yesArthritis Care &Research, Accepted Article.
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato   +27 more
wiley   +1 more source

Extraction Of Defensin Antimicrobial Peptide From SWISS-PROT Database Using Extended Boyer-More Algorithm. [PDF]

open access: yes, 2007
Antimicrobial Peptide (AMP) is a subset of protein that plays an essential role in innate immunity system. Researches on AMP are actively conducted in Immunology field where synthetics antibiotics are being developed. There are several classifications of
Ahamed Hassain Malim, N.H.   +1 more
core  

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

open access: yesAdvanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian   +6 more
wiley   +1 more source

Can We Prevent Antimicrobial Resistance by Using Antimicrobials Better?

open access: yes, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Germander Soothill   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy