Results 161 to 170 of about 351,657 (267)

Tellurium nanoparticles as antimicrobial agents for multi-drug-resistant infections. [PDF]

RSC Adv
Ajayi AS, Adanigbo P, Olaifa JT, Obaleye MO, Ofoka EA, Ukanwa SO, Duru P, Moshood F, Aigbodion AI, Ifijen IH.   +9 more
europepmc   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Thienopyrimidine scaffolds as promising antimicrobial agents: synthesis, biological evaluation, DFT analysis and molecular docking. [PDF]

RSC Adv
Sayed M, Naguib MA, Mohammed AAK, Hassanien R, Tolba MS, Ahmed M.   +5 more
europepmc   +1 more source

From Chatbots to Co‐Scientists: The Impact of Knowledge‐Generating AI (AI 4.0) on Healthcare and Research

Advanced Science, EarlyView.
This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley   +1 more source

Design, synthesis, and biological evaluation of novel imidazole-morpholinone hybrids as broad-spectrum antimicrobial agents: molecular docking, DFT, and ADMET studies. [PDF]

RSC Adv
Dave AJ, Joshi SS, Maheta JB, Bhola YO, Upadhyay J.   +4 more
europepmc   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Effects of non-chlorine antimicrobial agents on microbial diversity in yellow-feathered chickens during mixed precooling. [PDF]

Food Sci Anim Resour
Zhao Y, Huang T, Cai L, Wang H, Hu H, Li L, Yang Y, Li G, Li Z, Wang L, Wang P.   +10 more
europepmc   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Vacuolar-ATPase inhibitors are antimicrobial agents active against intracellular mycobacteria. [PDF]

Antimicrob Agents Chemother
Rankine-Wilson L, Shapira T, Felker J, Christofferson M, Sahile H, Chao J, Afshar H, Andersen RJ, Sun J, Av-Gay Y.   +9 more
europepmc   +1 more source