Results 251 to 260 of about 90,280 (287)

Cationic Antimicrobial Peptides in Penaeid Shrimp

Marine Biotechnology, 2010
Penaeid shrimp aquaculture has been consistently affected worldwide by devastating diseases that cause a severe loss in production. To fight a variety of harmful microbes in the surrounding environment, particularly at high densities (of which intensive farming represents an extreme example), shrimps have evolved and use a diverse array of ...
Anchalee, Tassanakajon, Piti, Amparyup, Kunlaya, Somboonwiwat, Premruethai, Supungul   +3 more
openaire   +3 more sources

Synergistic microbicidal effect of cationic antimicrobial peptides and teicoplanin against planktonic and biofilm-encased Staphylococcus aureus.

International Journal of Antimicrobial Agents, 2019
Antibiotic resistance and biofilm formation are the main reasons for failure in treatment of bacterial infections. This study aimed to identify synergistic combinations of conventional antibiotics and novel synthetic antimicrobial and antibiofilm ...
Bruce C Koppen, Patrick P. G. Mulder, L. de Boer, M. Riool, J. Drijfhout, S. Zaat   +5 more
semanticscholar   +1 more source

The Pharmacology of Radiolabeled Cationic Antimicrobial Peptides

Journal of Pharmaceutical Sciences, 2008
Cationic antimicrobial peptides are good candidates for new diagnostics and antimicrobial agents. They can rapidly kill a broad range of microbes and have additional activities that have impact on the quality and effectiveness of innate responses and inflammation.
Carlo P J M, Brouwer, Marty, Wulferink, Mick M, Welling   +2 more
openaire   +2 more sources

Antiendotoxin activity of cationic peptide antimicrobial agents

Infection and Immunity, 1996
The endotoxin from gram-negative bacteria consists of a molecule lipopolysaccharide (LPS) which can be shed by bacteria during antimicrobial therapy. A resulting syndrome, endotoxic shock, is a leading cause of death in the developed world. Thus, there is great interest in the development of antimicrobial agents which can reverse rather than promote ...
M, Gough, R E, Hancock, N M, Kelly
openaire   +2 more sources

Cationic Antimicrobial Peptides

BioDrugs, 2003
Many different types of organisms use antimicrobial peptides, typically 20-40 amino acids in length, for defence against infection. Most are capable of rapidly killing a wide range of microbial cells. They have been classified according to their active structures into six extensive groups.
openaire   +2 more sources

A Review of Antimicrobial Peptides: Defensins and Related Cationic Peptides

Veterinary Clinical Pathology, 1995
Cationic antimicrobial peptides are present throughout the plant and animal kingdoms and bear striking structural and functional similarities across species lines. They provide primitive, nonspecific means of combating a variety of bacteria, fungi, enveloped viruses, and protozoa.
Ellen W., Evans, Barry G., Harmon
openaire   +2 more sources

Cationic Antimicrobial Peptides—The Defensins

2006
The term defensin relates different families of host defense peptides (HDPs) in vertebrates, invertebrates, plants, and molds that display structural similarities based on a cystine stabilized antiparallel b-sheet core, with an N-terminal a-helical stretch in many members.
ANTCHEVA, Nikolinka, ZELEZETSKY, IGOR, TOSSI, ALESSANDRO   +2 more
openaire   +2 more sources

Cationic antimicrobial peptides: towards clinical applications

Expert Opinion on Investigational Drugs, 2000
Cationic antimicrobial peptides are important components of the innate immune defences of all species of life. Variants of these natural molecules have a broad range of antibiotic, antifungal, antiviral and anti-endotoxic activity. Two of these cationic peptides have shown signs of efficacy in early clinical trials of oral mucositis and the ...
openaire   +2 more sources

Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP)

Journal of Medicinal Chemistry, 2017
Teixobactin is a head to side chain cyclodepsipeptide that contains two positive charges. One is found in the cycle, as a result of the presence of the guanidino-unusual amino acid L-allo-End, while the other is at the N-terminal. Here we introduce 26 new Teixobactin analogues with an increasing number of positive charges.
Shimaa A. H. Abdel Monaim, Estelle J. Ramchuran, Ayman El-Faham, Fernando Albericio, Beatriz G. de la Torre   +4 more
openaire   +2 more sources

Antimicrobial Peptides and Macromolecules for Combating Microbial Infections: From Agents to Interfaces.

ACS Applied Bio Materials, 2022
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has evolved into a global health crisis, which drives researchers to continuously explore antimicrobial molecules and strategies to fight against drug-resistant ...
Luofeng Yu, Kunpeng Li, Jing Zhang, Haoyu Jin, Atif Saleem, Qing Song, Qingyan Jia, Peng Li   +7 more
semanticscholar   +1 more source