Results 91 to 100 of about 105,406 (254)

Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children

Clinical Epidemiology, 2022
Nils Skajaa,1– 4 Lise Gehrt,3,4 Heta Nieminen,5 Ida Laake,6 Hélène Englund,7 Ute Wolff Sönksen,8 Berit Feiring,6 Christine Stabell Benn,3,4,9 Lill Trogstad,6 Arto A Palmu,5 Signe Sørup1,3 1Department of Clinical Epidemiology, Aarhus University Hospital ...
Skajaa N, Gehrt L, Nieminen H, Laake I, Englund H, Sönksen UW, Feiring B, Benn CS, Trogstad L, Palmu AA, Sørup S   +10 more
doaj  

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

3D Printed Photon Shield Assembly for Low‐Noise Visual Stimulation During Two‐Photon Imaging in Mice

Advanced Materials Technologies, EarlyView.
We present the Photon Shield, an open‐hardware system for low‐noise two‐photon calcium imaging during visual stimulation in mice. Combining a 3D‐printed headplate and rail‐mounted shield substantially reduces stray‐light contamination, as quantitatively verified. Functional validation confirms reliable cortical responses. Open design files enable broad
Gergely Katona, Andrea Slézia, András Dávid, Ábel Petik, Dániel Hillier, István Ulbert, Attila Kaszás   +6 more
wiley   +1 more source

Linking Polyelectrolyte Modification and Enzyme‐Catalyzed Phenolic Acid Functionalization of Cellulose Fiber for Functional Foams

Advanced Materials Technologies, EarlyView.
Cellulose fibers functionalized using cationic poly(Dimethyldiallylammonium chloride) (polyDADMAC) and laccase‐mediated ferulic acid system are processed into foams using different surfactants (Anionic, cationic, and non‐ionic). Fiber–surfactant interactions influence foam stabilization and porous structure formation during convective drying, producing
Abirami Senthil, Sara Wallstén, Paul Christakopoulos, Ulrika Rova, Io Antonopoulou   +4 more
wiley   +1 more source

The impact of vaccination on the consumption of antimicrobials in pigs

, 2015
Antimicrobial agents are being used in modern swine production worldwide, generating concern with regards to the development of antimicrobial resistance. Identifying efficient alternatives has therefore become a subject of interest. The aim of this study was to explore the impact of vaccination as an alternative to antimicrobial consumption in pig ...
openaire   +2 more sources

Antimicrobial consumption and resistance in bacteria from humans and food‐producing animals

EFSA Journal
The fourth joint inter‐agency report on integrated analysis of antimicrobial consumption (AMC) and the occurrence of antimicrobial resistance (AMR) in bacteria from humans and food‐producing animals (JIACRA) addressed data obtained by the Agencies' EU ...
European Centre for Disease Prevention and Control (ECDC), European Food Safety Authority (EFSA), European Medicines Agency (EMA)   +2 more
doaj   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Could the effect of antimicrobials on antimicrobial resistance be saturated at high-antimicrobial consumption? A comparison of the MORDOR and ResistAZM studies

International Journal of Infectious Diseases
Antimicrobial resistance poses a considerable threat in high-antimicrobial-consumption populations, such as men who have sex with men (MSM) taking HIV pre-exposure prophylaxis. While the ResistAZM trial found no increase in macrolide resistance genes in MSM with gonorrhea after azithromycin treatment, the MORDOR trial observed an increase in these ...
Sheeba Santhini Manoharan-Basil, Zina Gestels, Saïd Abdelatti, Irith De Baetselier, Thibaut Vanbaelen, Armin Hinterwirth, Thuy Doan, Thomas Lietman, Chris Kenyon   +8 more
openaire   +3 more sources