Results 31 to 40 of about 105,406 (254)

Antimicrobials in mink – consumption and resistance patterns

, 2012
Use of antimicrobials in the mink production is of vital importance for controlling diseases. However, the increasing risk of developing antimicrobial resistant bacteria as a consequence of the medical treatment requires special attention to ensure continuing availability of antimicrobials for which the bacteria are fully susceptible.
M. Chriél, J. F. Harslund, T. H. Jensen, E. Jakobsen, A. S. Hammer, A. M. Lassen-Nielsen   +5 more
openaire   +1 more source

Kinetic Patterns of Antibiotic Consumption in German Acute Care Hospitals from 2017 to 2023

Antibiotics
Background: Antimicrobial consumption (AMC) patterns, besides prescribing behaviors, reflect the changing epidemiology of infectious diseases. Routine surveillance data have been used to investigate the development of AMC from 2017 to 2023 and the impact
Birgitta Schweickert, Niklas Willrich, Marcel Feig, Marc Schneider, Michael Behnke, Luis Alberto Peña Diaz, Christine Geffers, Imke Wieters, Karin Gröschner, Doreen Richter, Alexandra Hoffmann, Tim Eckmanns, Muna Abu Sin   +12 more
doaj   +1 more source

Antimicrobial resistance and antibiotic consumption in Mexican hospitals

Salud Pública de México, 2019
To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals.Antimicrobial susceptibility data from blood and urine isolates were collected. Defined daily dose (DDD) of antibiotic consumption/100 occupied beds (OBD) was calculated.Study period: 2016 and 2017. Of 4 382 blood isolates, E.
María Guadalupe Miranda-Novales, Karen Flores-Moreno, Yolanda López-Vidal, Mauricio Rodríguez-Álvarez, Fortino Solórzano-Santos, José Luis Soto-Hernández, Samuel Ponce de León-Rosales, UNCAR Network   +7 more
openaire   +4 more sources

Choosing New Therapies for Gonorrhoea: We Need to Consider the Impact on the Pan-Neisseria Genome. A Viewpoint

Antibiotics, 2021
The development of new gonorrhoea treatment guidelines typically considers the resistance-inducing effect of the treatment only on Neisseria gonorrhoeae. Antimicrobial resistance in N.
Chris Kenyon, Jolein Laumen, Sheeba Manoharan-Basil   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Risk Factor Analysis for Occurrence of Linezolid-Resistant Bacteria in the Digestive and Respiratory Tract of Food-Producing Animals in Belgium: A Pilot Study

Antibiotics
Linezolid is a critically important antimicrobial used in human medicine. While linezolid is not licensed for food-producing animals, the veterinary use of other antimicrobials, such as phenicols (e.g., florfenicol), could cross/co-select for linezolid ...
Michèle Driesen, Michaël Timmermans, Mickaël Cargnel, Xavier Simons, Maria-Eleni Filippitzi, Boudewijn Catry, Fabiana Dal Pozzo, Wannes Vanderhaeghen, Bénédicte Callens, Marc Dispas, Cécile Boland   +10 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Antimicrobial consumption and impact of antimicrobial stewardship programmes in long-term care facilities [PDF]

Clinical Microbiology and Infection, 2019
Antimicrobials are among the most frequently prescribed drugs in long-term care facilities (LTCFs). Implementation of antimicrobial stewardship programmes (ASPs) is often challenging because of scarce data in this setting.This narrative review aimed to provide data about antibiotic consumption in LTCFs and the need, implementation, and organization of ...
Falcone, M., Paul, M., Yahav, D., Orlando, G., Tiseo, G., Prendki, Virginie, Güerri-Fernández, R., Gavazzi, G., Mutters, N.T., Cookson, B., Tinelli Marco, M., Study Group for Infections in the Elderly (ESGIE)   +11 more
openaire   +5 more sources

Decline in Antimicrobial Consumption and Stagnation in Reducing Disease Burden due to Antimicrobial Resistance in Japan

Infectious Diseases and Therapy, 2023
Antimicrobial resistance (AMR) is a major global health threat. While antimicrobial consumption (AMC) in Japan substantially decreased after implementation of the AMR National Action Plan, the disease burden due to AMR seems to be unchanged. The main objective of this study is to examine the relationship between AMC and the disease burden due to AMR in
Shinya Tsuzuki, Ryuji Koizumi, Nobuaki Matsunaga, Norio Ohmagari   +3 more
openaire   +4 more sources