Results 41 to 50 of about 105,406 (254)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Impact of an Antimicrobial Stewardship Program Intervention Associated with the Rapid Identification of Microorganisms by MALDI-TOF and Detection of Resistance Genes in ICU Patients with Gram-Negative Bacteremia

Antibiotics, 2022
Combination of strategies for rapid diagnostics tests (RDT) with real-time intervention could improve patient outcomes. We aimed to assess the impact on clinical outcomes, antimicrobial consumption, and costs in patients with gram-negative bacteremia. We
Aléia Faustina Campos, Tiago Arantes, Amanda Magalhães Vilas Boas Cambiais, Ana Paula Cury, Camila Guimarães Tiroli, Flávia Rossi, Luiz Marcelo Sa Malbouisson, Silvia Figueiredo Costa, Thaís Guimarães   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Antimicrobial consumption and antimicrobial resistance: a snapshot of an Italian neuromuscular rehabilitation center. [PDF]

The new microbiologica, 2017
The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was
Barberi, Giuseppina, De Cola, Maria Cristina, Dell'Utri, De Cola, Melardi, Sara, Alagna, Bernardo, Bramanti, Placido, Cascio, Antonio   +6 more
openaire   +3 more sources

Antimicrobial resistance genes in raw milk for human consumption [PDF]

Scientific Reports, 2020
Abstract The increasing prevalence of antimicrobial resistance (AMR) is a significant threat to global health. More and more multi-drug-resistant bacterial strains cause life-threatening infections and the death of thousands of people each year.
Tóth, Adrienn Gréta, Csabai, István, Krikó, Eszter, Tőzsér, Dóra, Maróti, Gergely, Patai, Árpád V., Makrai, László, Szita, Géza, Solymosi, Norbert   +8 more
openaire   +3 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Point Prevalence Survey of Antibiotic Use in Latin American Hospitals: 2022–2023

Antibiotics
Background: Antimicrobial resistance (AMR) is a public health challenge, exacerbated by the inappropriate use of antibiotics (ABs) and the lack of standardized surveillance in healthcare settings.
Paola Lichtenberger, Gabriel Levy-Hara, Robin Rojas-Cortés, Tatiana Orjuela, Jose Pablo Diaz-Madriz, Pilar Ramon-Pardo, Jose Luis Bustos, Anahí Dreser, Tania Herrera, Marcela Pilar Rojas-Diaz, Giovanna Huaquipaco, Didia Sagastume, Jose Luis Castro, on behalf of the Latin American PPS Group   +13 more
doaj   +1 more source

Abundance and Antimicrobial Resistance of Three Bacterial Species along a Complete Wastewater Pathway

Microorganisms, 2019
After consumption, antibiotic residues and exposed bacteria end up via the feces in wastewater, and therefore wastewater is believed to play an important role in the spread of antimicrobial resistance (AMR). We investigated the abundance and AMR profiles
Ilse Verburg, Silvia García-Cobos, Lucia Hernández Leal, Karola Waar, Alex W. Friedrich, Heike Schmitt   +5 more
doaj   +1 more source

Control of Healthcare-Associated Carbapenem-Resistant Acinetobacter baumannii by Enhancement of Infection Control Measures

Antibiotics, 2022
Antimicrobial stewardship and infection control measures are equally important in the control of antimicrobial-resistant organisms. We conducted a retrospective analysis of the incidence rate of hospital-onset carbapenem-resistant Acinetobacter baumannii
Shuk-Ching Wong, Pui-Hing Chau, Simon Yung-Chun So, Germaine Kit-Ming Lam, Veronica Wing-Man Chan, Lithia Lai-Ha Yuen, Christine Ho-Yan Au Yeung, Jonathan Hon-Kwan Chen, Pak-Leung Ho, Kwok-Yung Yuen, Vincent Chi-Chung Cheng   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source