Results 51 to 60 of about 105,406 (254)

Analysis of antimicrobial consumption and cost in a teaching hospital

Journal of Infection and Public Health, 2014
The aim of this study is to compare the periods before and after the intervention applied using the ATC/DDD method in order to ascertain the rational use of antibiotics in a newly established hospital.The appropriateness of the hospital's antibiotic use, consumption rates and the costs were calculated and compared with other hospitals.
Bozkurt, Fatma, Kaya, Safak, Tekin, Recep, Gulsun, Serda, Deveci, Ozcan, Dayan, Saim, Hosoglu, Salih   +6 more
openaire   +3 more sources

A Point Prevalence Survey of Antimicrobial Use in Second-Level Mexican Hospitals: A Multicenter Study

Antibiotics
In 2018, the WHO published a methodology for conducting a point prevalence survey (PPS) of antibiotic use in hospitals. The aim of this study is to report the use of antibiotics in six second-level hospitals in Mexico using this methodology.
German Alberto Venegas-Esquivel, María Guadalupe Berumen-Lechuga, Carlos José Molina-Pérez, Rodolfo Norberto Jimenez-Juarez, Enna Guadalupe Villanueva-Cabrera, David Vargas-González, Gonzalo Santos-González, Rebeca Pamela Velázquez Pérez, Mariana Hernández Navarrete, Celene Corral-Rico, Natali Robles-Ordoñez, Juan Manuel Lara-Hernández, Helen’s Irais Sánchez Mendoza   +12 more
doaj   +1 more source

Extrapolating Antibiotic Sales to Number of Treated Animals: Treatments in Pigs and Calves in Switzerland, 2011–2015

Frontiers in Veterinary Science, 2019
To evaluate the contribution of antimicrobial use in human and veterinary medicine to the emergence and spread of resistant bacteria, the use of these substances has to be accurately monitored in each setting. Currently, various initiatives collect sales
Rosa Stebler, Rosa Stebler, Luís P. Carmo, Dagmar Heim, Hanspeter Naegeli, Klaus Eichler, Cedric R. Muentener   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Understanding Antibiotic Use in Companion Animals: A Literature Review Identifying Avenues for Future Efforts

Frontiers in Veterinary Science, 2021
Addressing antibiotic use is essential to tackle antimicrobial resistance, a major human and animal health challenge. This review seeks to inform stewardship efforts in companion animals by collating research insights regarding antibiotic use in this ...
Alice C. Tompson, Ana L. P. Mateus, Dave C. Brodbelt, Clare I. R. Chandler   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Antimicrobial consumption at a university hospital in Turkey

African Journal of Microbiology Research, 2012
Excessive antibiotic use is a challenging topic because of the total annual expenditure and the high resistance against antimicrobials in Turkey. A point-prevalence study was performed to evaluate the daily antibiotic consumption and the cost. Data were collected by infectious diseases consultants on 30 January, 2009 and 28 January 2010.
Akalın, Şerife, Çaylak, Selmin, Özen, Güneş, Turgut, Hüseyin   +3 more
openaire   +4 more sources

Association Between Antimicrobials and Pump Proton Inhibitors Consumption with the Incidence of Nosocomial Clostridiodes difficile Infection in High Complexity Hospitals in Costa Rica

Antibiotics
Background: Exposure to antimicrobials and Proton Pump Inhibitors (PPIs) are modifiable risk factors for nosocomial Clostridiodes difficile infection (CDI). We investigated the association between these agents and nosocomial CDI over five years. Methods:
Cristina Fernández-Barrantes, Allan Ramos-Esquivel, Luis Esteban Hernández-Soto, Manuel Ramírez-Cardoce, Luis David Garro-Zamora, José Castro Cordero, Santiago Grau   +6 more
doaj   +1 more source

Evaluation of antibiotic consumption using WHO -antimicrobial consumption tool and AWaRe classification. [PDF]

J Family Med Prim Care
ABSTRACT Introduction: Antimicrobial resistance is a public health concern with global ramifications. Antibiotic misuse and overuse, are rampant in our country but more alarming is the data on the use of antibiotics primarily because of lack of access is another threat.
Birdie Wahlang J, Syiem RP, Sarkar C, Lyngdoh NM, Tiewsoh I, Brahma DK, Surong A, Langstieh AJ.   +7 more
europepmc   +4 more sources