Results 71 to 80 of about 4,493,796 (297)

An Emptying Quiver: Antimicrobial Drugs and Resistance

Emerging Infectious Diseases, 2005
Since the dawn of the antibiotic era, resistance has shadowed the success of infectious disease therapy. In his 1945 Nobel Prize acceptance speech, Alexander Fleming noted the danger of resistance: "It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same
J. Todd Weber, Patrice Courvalin
openaire   +3 more sources

Wearable Smart Patches on Sustainable Chitosan With Reversible Microbial Growth‐Inhibitory Properties

Advanced Functional Materials, EarlyView.
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti, Kubra Kocak, Andrea Michel, Enrico Cavarzerani, Ali Raza, Petr Rohzin, Nouha Loudhaief, Saimir Frroku, Nicolò Baldovin, Hazrat Bilal, Alvise Perosa, Maurizio Selva, Flavio Rizzolio, Luca Sbuelz, Sabrina Tamburini, Domenico De Fazio, Giovanni Antonio Salvatore   +16 more
wiley   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae. [PDF]

, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Holden, MTG, Atherton, Tom, Rogers, Jon, Maskell, Duncan J, Chaudhuri, RR, Tucker, AW, Rycroft, Andrew N, Rycroft, AN, Walker, S, Tucker, A W, Weinert, LA, Weinert, Lucy A, Wren, Brendan W, Atherton, T, Bossé, J T, BRaDP1T Consortium, Chaudhuri, R R, Bossé, Janine T, Tucker, Alexander W, Chaudhuri, Roy R, Oshota, Olusegun, Walker, Stephanie, Langford, PR, Crespo, R F, Rogers, J, Rycroft, A N, Oshota, O, Fernandez Crespo, R, Wren, BW, Fernandez Crespo, Roberto, Holden, M T G, Williamson, Susanna M, Williamson, S M, Maskell, D J, Wren, B W, Williamson, SM, Weinert, L A, Li, Yanwen, Langford, P R, Maskell, DJ, Langford, Paul R, Holden, Matthew, Li, Y, Holden, Matt TG, Bosse, J, Holden, Matthew; id_orcid   +45 more
core   +1 more source

Advancing SafeWax, A Bio‐Inspired Superhydrophobic Coating, Toward Sustainable and Climate‐Resilient Crop Protection

Advanced Functional Materials, EarlyView.
This study advances SafeWax, a bio‐inspired, fatty‐acids‐based superhydrophobic coating, by identifying an agriculturally compliant solvent and revealing how solvent‐controlled Fatty acid crystallization governs the coating's microscopic structure and performance.
Niv Ben‐Arie, Iryna Polishchuk, Franziska Tauber, Coralie Schneider, Elena Prudnikov, Alessia Calora, Silvia Milita, Simona Fermani, Mireia Alejandra Ibanez Revert, Ilaria Filippetti, Claudio Ratti, Matthias Kellermeier, Markus Rueckel, Boaz Pokroy   +13 more
wiley   +1 more source

Drug Resistance in Antimicrobial Therapy [PDF]

Archives of Pediatrics & Adolescent Medicine, 1975
This book is published as one of a series of monographs called the "American Lectures in Living Chemistry," which is somewhat strange because the authors are British and chemistry is given scant attention. Lowbury and Ayliffe are physicians as well as clinical bacteriologists and have been prominent reporters of the scope of microbial resistance during
  +5 more sources

Danish Integrated Antimicrobial Resistance Monitoring and Research Program

Emerging Infectious Diseases, 2007
Resistance to antimicrobial agents is an emerging problem worldwide. Awareness of the undesirable consequences of its widespread occurrence has led to the initiation of antimicrobial agent resistance monitoring programs in several countries.
Anette M. Hammerum, Ole E. Heuer, Hanne-Dorthe Emborg, Line Bagger-Skjøt, Vibeke F. Jensen, Anne-Marie Rogues, Robert L. Skov, Yvonne Agersø, Christian T. Brandt, Anne Mette Seyfarth, Arno Muller, Karin Hovgaard, Justin Ajufo, Flemming Bager, Frank M. Aarestrup, Niels Frimodt-Møller, Henrik C. Wegener, Dominique L. Monnet   +17 more
doaj   +1 more source

Global trends in antimicrobial resistance on organic and conventional farms

Scientific Reports, 2023
The important hypothesis that organic livestock management reduces the prevalence of antimicrobial resistance is either fiercely supported or bitterly contested.
Eldon O. Ager, Tamilie Carvalho, Erin M. Silva, Steven C. Ricke, Jessica L. Hite   +4 more
doaj   +1 more source

Selection and evolution of resistance to antimicrobial drugs [PDF]

IUBMB Life, 2014
AbstractThe overuse and misuse of antibiotics over many years has selected a high frequency of resistance among medically important bacterial pathogens. The evolution of resistance is complex, frequently involving multiple genetic alterations that minimize biological fitness costs and/or increase the resistance level. Resistance is selected at very low
openaire   +2 more sources

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source