Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C. +3 more
core +1 more source
Importance of antimicrobial stewardship in solid organ transplant recipients: An ESCMID perspective. [PDF]
BackgroundIn the last decades, solid organ transplantation (SOT) has emerged as an important method in the management of chronic kidney, liver, heart, and lung failure.
Supported by the ESCMID Study Group for Antimicrobial Stewardshi +22 more
core +1 more source
Evaluation of Antimicrobial Efficacy of Antibiotics and Calcium Hydroxide against Enterococcus faecalis Biofilm in Dentine [PDF]
The objective of this study was to investigate the antimicrobial efficacy of erythromycin, oxytetracycline and calcium hydroxide [Ca(OH)(2)] against Enterococcus faecalis biofilm in dentine. E.
Hamimah, H. +3 more
core +1 more source
Aim: The current study aimed to compare and evaluate the antimicrobial efficacy of graphene oxide (GO) silver nanoparticle (AgNp) as root canal irrigant (RCI) with other RCIs in maxillary anterior teeth with necrotic pulp.
Annapoorani Sevagaperumal +5 more
doaj +1 more source
Production of silver-loaded zeolites and investigation of their antimicrobial activity [PDF]
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyThe production of silver-loaded zeolites either by ion exchange method or by isomorphous substitution of silver ions ...
Kwakye-Awuah, Bright
core +3 more sources
Niacinamide Antimicrobial Efficacy and Its Mode of Action via Microbial Cell Cycle Arrest
Niacinamide is a versatile compound widely used in the personal care industry for its ample skin benefits. As a precursor to nicotinamide adenine dinucleotide (NAD+), essential for ATP production and a substrate for poly-ADP-ribose polymerase-1 (PARP-1),
Noa Ziklo +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Targeting antimicrobial drug resistance with marine natural products
The rise and spread of antimicrobial resistance represents one of the most pressing health issues of today. Antimicrobial resistance in micro-organisms can arise due to a multiplicity of factors, including perme- ability changes in the cell membrane ...
Sousa, E. +4 more
core +1 more source
In vivo antimicrobial potential of orthodontic bands coated with green-synthesized zinc oxide, titanium oxide, and their nanocomposites [PDF]
Background. Orthodontic bands are prone to biofilm accumulation, leading to dental plaque formation and increased risk of caries. Incorporating antimicrobial coatings on these bands can help reduce microbial colonization.
Mary Sheloni Missier +3 more
doaj +1 more source

