Results 41 to 50 of about 2,148,381 (250)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Antimicrobial resistance surveillance in Europe 2013: Annual Report of the European Antimicrobial Resistance Surveillance Network (EARS-Net) [PDF]

, 2014
Portugal - EARS-Net Management Team & National representatives of EARS-Net (Manuela Caniça, José Artur Paiva, Vera Manageiro, Eugénia Ferreira)The results presented in this report are based on antimicrobial resistance data from invasive isolates reported
European Antimicrobial Resistance Surveillance Network (EARS-Net)
core   +1 more source

Bacterial Resistance to Antimicrobial Agents

, 2021
Bacterial pathogens as causative agents of infection constitute an alarming concern in the public health sector. In particular, bacteria with resistance to multiple antimicrobial agents can confound chemotherapeutic efficacy towards infectious diseases ...
Nicholas Wenzel, Sanath H. Kumar, Manisha Ojha, Jerusha Stephen, Alberto J. Hernandez, Leslie M. Sanford, Manjusha Lekshmi, Ammini Parvathi, Manuel F. Varela   +8 more
core   +1 more source

Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems

Journal of Pharmacy and Bioallied Sciences
Objective: To compare the antimicrobial effectiveness of erbium-doped yttrium-aluminum-garnet (Er: YAG) laser, ozone therapy, photodynamic therapy (PDT), and sodium hypochlorite against endodontic pathogens.
Hitesh Chohan, Sanjana Khullar, Ria H Patel, Jyotirmayee Rath, Sameera Mohammed, Savadamoorthi Kamatchi Subramani   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Vitamin D, innate immunity and outcomes in community acquired pneumonia [PDF]

, 2011
We investigated the associations between vitamin D status, the antimicrobial peptides cathelicidin and beta defensin-2 and outcomes in community acquired pneumonia.
Karalus, Noel, LEONG LEOW, Cursons, Raymond T., RAY CURSONS, Hancox, Robert J., Leow, Leong, NOEL KARALUS, ROBERT J. HANCOX, TALIA SIMPSON, Leong, Talia   +9 more
core   +1 more source

Design and Optimization of Sustained-Release Dental Implants for Targeted Periodontal Drug Delivery

Journal of Pharmacy and Bioallied Sciences
Background: Periodontal therapy often requires sustained and targeted drug delivery to enhance therapeutic outcomes and minimize systemic side effects.
Silpi Chatterjee, Daya Shankar, Yagyesh Mehta, Swamini Ajay Shete, Asim Mustafa Khan, Ankita Kumari   +5 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Investigation of the Potential of Nanoparticles as a New Drug Delivery System for Endodontic Treatment

Journal of Pharmacy and Bioallied Sciences
Background: The application of nanoparticles in endodontic treatment presents a novel approach to drug delivery, potentially enhancing the efficacy of therapeutic agents.
Abdul A. K. Kader, Sandeep Chandran, K. K. Ridhun Unnikrishnan, Nikita A. Mannur, Anusar Gupta, Savadamoorthi Kamatchi Subramani   +5 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source