Results 61 to 70 of about 2,148,381 (250)

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]

, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Francisco J. L. Aragão (132479), Jacques Nicoli (132482), Guilherme D Brand, Tinoco Maria L. P., Guilherme D. Brand (132470), Sharon M Kelly, Maria L P Tinoco, Brand, G.D., Jacques Nicoli, Mariana T. Q. Magalhães (132473), Francisco J L Aragão, Tinoco, M.L.P., Alan Cooper (9827), Cooper Alan, Nicoli, J., Carlos Bloch, Kelly Sharon M., Magalhães, M.T.Q., Sharon M. Kelly (132485), Kelly, S., Aragão, F.J.L., Bloch Jr, C., Brand Guilherme D., Aragão Francisco J. L., Maria L. P. Tinoco (132476), Magalhães Mariana T. Q., Alan Cooper, Bloch Carlos, Cooper, A., Mariana T Q Magalhães, Nicoli Jacques, Carlos Bloch Jr (132488)   +31 more
core   +1 more source

Sprayable Hybrid Gel with Cannabidiol, Hyaluronic Acid, and Colloidal Silver: A Multifunctional Approach for Skin Lesion Therapy

Pharmaceutics
Background/Objectives: This study presents the development and characterization of a novel thermoresponsive hydrogel composed of hyaluronic acid (HA), poloxamer 407, cannabidiol (CBD), and colloidal silver (Ag), designed for topical antimicrobial therapy.
Geta-Simona Cîrloiu (Boboc), Adina-Elena Segneanu, Ludovic Everard Bejenaru, Marius Ciprian Văruţ, Roxana Maria Bălăşoiu, Daniela Călina, Andreea-Cristina Stoian, Georgiana Băluşescu, Dumitru-Daniel Herea, Maria Viorica Ciocîlteu, Andrei Biţă, George Dan Mogoşanu, Cornelia Bejenaru   +12 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Comparative evaluation of antibacterial efficacy of sequential herbal irrigation with conventional irrigation in endodontic therapy of primary teeth: A randomized controlled trial

Journal of Indian Society of Pedodontics and Preventive Dentistry
Background: Successful endodontic therapy in primary teeth relies on effective microbial control. Although conventional irrigants are effective, they pose risks such as cytotoxicity, unpleasant taste, and tissue irritation.
Shrikant Bhujangrao Kendre, Anuja U. Bhatane, Mahesh Vilasrao Dadpe, Yogesh Jagannath Kale, Prasanna Trambakrao Dahake   +4 more
doaj   +1 more source

Evaluation of antibacterial and antifungal properties of selected mouthwashes: in vitro studies

Current Issues in Pharmacy and Medical Sciences, 2021
Introduction. Mouthwashes should include antimicrobial compounds to inhibit microorganism multiplication, thus the formation and development of dental plaque.
Olejnik Ewa, Biernasiuk Anna, Malm Anna, Szymanska Jolanta   +3 more
doaj   +1 more source

Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals

Advanced Functional Materials, EarlyView.
The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner, Julian Fanelli, Vinh Xuan Truong, Rob Jones, Jens Gaitzsch, Christopher Barner‐Kowollik   +5 more
wiley   +1 more source

An evaluation of antimicrobial stewardship in community pharmacy [PDF]

, 2016
This study investigated several aspects of antimicrobial stewardship by gathering information from community pharmacists and members of the public. The aim was to identify how community pharmacists implement antimicrobial stewardship guidelines and ...
Mellor, Callan, Hancock, Laura Jade
core   +2 more sources

A Review and Comparative Study of Preservative Efficacy Test in the United States, European, Indian, and Japanese Pharmacopeias and Implications for Asian Pharmacopeias

Journal of Medical Microbiology and Infectious Diseases
Introduction: The preservative efficacy test (PET) is a critical tool for assessing the ability of antimicrobial preservatives to prevent microbial contamination in pharmaceutical products, ensuring their safety and stability during production and ...
Sara Sajjadi, Fatemeh Shafizadeh, Somayeh Hallaj-Nezhadi   +2 more
doaj   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source