Results 141 to 150 of about 3,822,401 (336)

Thiolated Hyaluronic Acid: A Gateway for Targeted Killing of Staphylococcus aureus on the Race for Surface Colonization

Advanced Healthcare Materials, EarlyView.
Thiolated hyaluronic acid (HAMS) synthesized and characterized by NMR, solubility, thiol content, and pKa, is degraded by Staphylococcal hyaluronate lyase but not by mammalian hyaluronidase. Coating polyphosphate–M23 phage endolysin nanoparticles (M23‐PP) with HAMS confers Staphylococcus aureus responsiveness.
Mariana Blanco Massani, Susanne Meile, Annabelle Knoll, David Gintsburg, Ilaria Polidori, Anna Seybold, Débora C. Coraça‐Huber, Martin J. Loessner, Gergely Kali, Mathias Schmelcher, Szczepan Zapotoczny, Andreas Bernkop‐Schnürch   +11 more
wiley   +1 more source

Emergence and genetic characterization of KLUC-3 extended-spectrum β-lactamase-producing Escherichia coli ST95 High-Risk clone causing nosocomial infection in Japan

Journal of Global Antimicrobial Resistance
: Objectives: KLUC β-lactamase is a minor extended-spectrum β-lactamase (ESBL) derived from chromosome-encoded cefotaximase in Kluyvera cryocrescens. This study aimed to characterize the genetic context of KLUC-3-producing Escherichia coli and blaKLUC-3-
Wataru Hayashi, Shizuo Kayama, Liansheng Yu, Chiemi Tokushige, Makiko Yuki, Yo Sugawara, Koji Yahara, Motoyuki Sugai   +7 more
doaj   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81

Scientific Reports
Fluoroquinolone-resistant (FQs-R) microorganisms causing infectious complications after ultrasound-guided needle biopsy of the prostate (TRUS-BP) have become an important challenge in healthcare settings globally, questioning the continued utility of FQ ...
Rehaiem Amel, Bouzouita Abderrazek, Ferjani Sana, Saadi Ahmed, Zrelli Mariem, Kanzari Lamia, Ferjani Asma, Mohamed Riadh Ben Slama, Boutiba Ben Boubaker Ilhem   +8 more
doaj   +1 more source

Formulating Smart All‐in‐One Chitosan Hydrogel for High Performance Wound Dressing

Advanced Healthcare Materials, EarlyView.
An innovative approach to fabricating a thermosensitive, highly swelling, degradable, and antibacterial hydrogel composed of a chitosan‐g‐NIPAAm/PVA/PVP copolymer, integrated with AgNPs, for use in wound dressing applications. The hydrogel demonstrates enhanced performance, accelerating the wound healing process.
Chia‐Chi Lin, Andi Magattang Gafur Muchlis, Ren‐Jei Chung, Ssu Yu Huang, Michal Martinka, Syang‐Peng Rwei, Aivaras Kareiva, Jen‐Chang Yang, Chun Che Lin   +8 more
wiley   +1 more source

30-Day Mortality in Candida auris Cases in Tennessee from 2022-2023

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Candida auris, a multi-drug resistant fungal pathogen, was first detected in Tennessee healthcare facilities in 2022. C. auris can colonize a patient’s skin and cause clinical infection.
Cherlly Bailey, Cody Rocha, Simone Godwin, Melphine Harriott   +3 more
doaj   +1 more source

Editorial: Antimicrobial resistance and antimicrobial alternatives

Frontiers in Medicine, 2023
Marwan Osman, Marwan Osman, Imad Al Kassaa, Khaled El Omari, Khaled El Omari, Issmat I. Kassem   +5 more
openaire   +3 more sources

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Lindfors CES, Arts JJC, Lindfors NC
wiley   +1 more source

Injectable Deep Eutectic Solvent‐Based Ionic Gel With Rapid Gelation and Broad Hemostatic Functionality

Advanced Healthcare Materials, EarlyView.
An injectable deep eutectic solvent‐based ionic gel is developed for rapid in situ gelation and broad‐spectrum hemostatic functionality. The material combines high mechanical strength, strong tissue adhesion, and antibacterial activity, demonstrating potential as an advanced biofunctional gel for emergency bleeding control and wound care.
Jia‐Yu Yang, En‐Yu Zhou, Ting‐Hui Cheng, Pin‐Hung Liu, Wen‐Ching Hsieh, Hui‐Ching Cheng, Yi‐Kai Hong, Yu‐Chen Lin, Yi‐Chiung Hsu, Chao‐Chun Yang, Chao‐Kai Hsu, Li‐Chieh Kuo, Shang‐Chin Hsieh, Cheng‐Hsin Chuang   +13 more
wiley   +1 more source

Antimicrobial resistance of Pasteurella multocida strains isolated from pigs between 2010 and 2016

, 2018
Yoon‐Hee Oh, Dong Chan Moon, Young Ju Lee, Bang‐Hun Hyun, Suk‐Kyung Lim   +4 more
openalex   +1 more source