Results 101 to 110 of about 189,957 (277)

Estimation of the impact of hospital-onset SARS-CoV-2 infections on length of stay in English hospitals using causal inference

BMC Infectious Diseases, 2022
Background From March 2020 through August 2021, 97,762 hospital-onset SARS-CoV-2 infections were detected in English hospitals. Resulting excess length of stay (LoS) created a potentially substantial health and economic burden for patients and the NHS ...
James Stimson, Koen B. Pouwels, Russell Hope, Ben S. Cooper, Anne M. Presanis, Julie V. Robotham   +5 more
doaj   +1 more source

Antibiotic dispensing practices during COVID-19 and implications for Antimicrobial Resistance (AMR): Parallel mystery client studies in Uganda and Tanzania [PDF]

, 2022
Emmanuel Olamijuwon, Eveline T. Konje, Catherine Kansiime, Mike Kesby, Katherine Keenan, Stella Neema, Benon Asiimwe, Stephen E. Mshana, Martha F. Mushi, Olga Loza, Benjamin Sunday, Alison Sandeman, Derek J. Sloan, Fernando Benitez‐Paez, Joseph R. Mwanga, Wilber Sabiiti, Matthew T. G. Holden, Joel Bazira, Christine Muhumuza, Ivan Muhwezi, Kathryn J. Fredricks   +20 more
openalex   +1 more source

Effective elimination of Staphylococcal contamination from hospital surfaces by a bacteriophage-probiotic sanitation strategy: a monocentric study. [PDF]

, 2019
Persistent contamination of hospital surfaces and antimicrobial resistance (AMR) are recognized major causes of healthcare-associated infections (HAI). We recently showed that a probiotic-based sanitation (PCHS) can stably decrease surface pathogens and ...
BISI, Matteo, CASELLI, Elisabetta, D'ACCOLTI, Maria, LANZONI, Luca, MAZZACANE, Sante, SOFFRITTI, IRENE, VOLTA, Antonella   +6 more
core   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

Advanced Science, EarlyView.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]

, 2018
This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau, Ivanova, Kristina Dimitrova, Ramon Portés, Eva, Tzanov, Tzanko   +3 more
core   +2 more sources

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Antimicrobial stewardship and infection prevention-leveraging the synergy: A position paper update. [PDF]

, 2018
Summary The issues surrounding the prevention and control of infections are intrinsically linked with the issues associated with the use of antimicrobial agents and the proliferation and spread of MDROs.
Ashley, Elizabeth S. Dodds, Cosgrove, Sara E., Fakih, Mohamad G., Manning, Mary Lou, Moody, Julia A., Myers, Frank E., Schweon, Steve J., Septimus, Edward J.   +7 more
core   +2 more sources

Indole contributes to tetracycline resistance via the outer membrane protein OmpN in Vibrio splendidus [PDF]

, 2020
As an interspecies and interkingdom signaling molecule, indole has recently received attention for its diverse effects on the physiology of both bacteria and hosts. In this study, indole increased the tetracycline resistance of Vibrio splendidus.
Guo, Ming, Li, Chenghua, Lv, Zhimeng, Shao, Yina, Zhang, Shanshan, Zhang, Weiwei, Zhao, Xuelin   +6 more
core   +1 more source

Antimicrobial resistance (AMR) and plant-derived antimicrobials (PDAms) as an alternative drug line to control infections

3 Biotech, 2013
Infectious diseases caused by antimicrobial-resistant microbes (ARMs) and the treatment are the serious problems in the field of medical science today world over.
J. Srivastava, H. Chandra, A. Nautiyal, S. Kalra   +3 more
semanticscholar   +1 more source

A Multicenter Validation of a Fully Automated Chemiluminescence Immunoassay for Plasma Elafin in Psoriasis Diagnosis and Severity Assessment

Advanced Science, EarlyView.
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi, Meng Xu, Ling Han, Zhining Dong, Ruimin Liu, Xiaomei Zhang, Di Hu, Chuanjian Lu, Xiaobo Yu   +8 more
wiley   +1 more source