Results 71 to 80 of about 226,602 (286)

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Identification, Genotyping and Antimicrobial Susceptibility Testing of Brucella spp. Isolated from Livestock in Egypt [PDF]

, 2019
Brucellosis is a highly contagious zoonosis worldwide with economic and public health impacts. The aim of the present study was to identify Brucella (B.) spp. isolated from animal populations located in different districts of Egypt and to determine their
El-Adawy, Hosny, Elschner, Mandy C., Khan, Aman Ullah, Melzer, Falk, Moawad, Amira A., Neubauer, Heinrich, Ramadan, Eman Shawkat, Roesler, Uwe, Sayour, Ashraf E., Shell, Waleed S.   +9 more
core   +1 more source

All‐Aqueous Pullulan Fibers Enabling Visible‐to‐Near‐Infrared Waveguiding with Mechanical and Thermal Resilience

Advanced Functional Materials, EarlyView.
Pullulan, a biomass‐derived polysaccharide, is transformed into transparent optical fibers using a solvent‐free borax hydrogel‐spinning method. The fibers outperform PMMA with ≈200 MPa tensile strength and 200 °C stability, while uniquely guiding visible‐to‐NIR light and enabling additive‐free humidity sensing.
Yuya Fukata, Aayush Kumar Jaiswal, Ari Hokkanen, Hannes Orelma, Tadahisa Iwata   +4 more
wiley   +1 more source

Rapid antibiotic susceptibility testing from blood culture bottles with species agnostic real-time polymerase chain reaction.

PLoS ONE, 2018
Development and implementation of rapid antimicrobial susceptibility testing is critical for guiding patient care and improving clinical outcomes, especially in cases of sepsis.
Tucker Maxson, Candace D Blancett, Amanda S Graham, Christopher P Stefan, Timothy D Minogue   +4 more
doaj   +1 more source

Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli: comparison between Etest and a broth dilution method

Annals of Clinical Microbiology and Antimicrobials, 2018
Background Campylobacter is a leading cause of foodborne gasteroenteritis worldwide. Antimicrobial susceptibility testing for Campylobacter spp. is not routinely performed by most clinical laboratories.
Maya Azrad, Linda Tkhawkho, Natalia Isakovich, Orna Nitzan, Avi Peretz   +4 more
doaj   +1 more source

Antibiotic susceptibility and high prevalence of extended spectrum beta-lactamase producing Escherichia coli in iranian broilers [PDF]

, 2016
Extended-spectrum β-lactamase (ESBL) producing Escherichia coli have rapidly spread worldwide and cause serious threats for public health. The study was conducted to determine the antibiotic resistance and characterization of ESBL producing E.
Khoshbakht, R., Raeisi, M., Seifi, S.
core  

Evaluation of the efficacy and safety of high dose short duration enrofloxacin treatment regimen for uncomplicated urinary tract infections in dogs. [PDF]

, 2012
BackgroundUncomplicated urinary tract infections (UTI) in dogs usually are treated with antimicrobial drugs for 10-14 days. Shorter duration antimicrobial regimens have been evaluated in human patients.HypothesisA high dose short duration (HDSD ...
Chew, DJ, Daniels, JB, Irom, S, Keil, D, Settje, T, Smith, A, Sykes, JE, Wang, Y, Westropp, JL   +8 more
core   +1 more source

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

Enrofloxacin-based therapeutic strategy for the prevention of endometritis in susceptible mares [PDF]

, 2010
Enrofloxacin (EFX) is often used empirically to prevent uterine infections in mares in order to improve efficiency on Commercial Embryo Transfer Farms.
Confalonieri, Alejandra, Fumuso, Elida Ana, García, J., González, C., Moreno, Laura Susana, Rivulgo, Virginia Margarita, Sanchez Bruni, Sergio Fabian, Sparo, Mónica Delfina   +7 more
core   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source