Results 51 to 60 of about 2,981,481 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Metabolism of Microbiota in Critical Illness (Review and Postulates)

Общая реаниматология, 2019
This article discusses the importance of eliciting the mechanisms of action and the metabolism of microbiota in the critically ill patients, as well as the role of nutrition specialist in the management of these patients.In critically ill patients the ...
Natalia V. Beloborodova
doaj   +1 more source

Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]

, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Francisco J. L. Aragão (132479), Jacques Nicoli (132482), Guilherme D Brand, Tinoco Maria L. P., Guilherme D. Brand (132470), Sharon M Kelly, Maria L P Tinoco, Brand, G.D., Jacques Nicoli, Mariana T. Q. Magalhães (132473), Francisco J L Aragão, Tinoco, M.L.P., Alan Cooper (9827), Cooper Alan, Nicoli, J., Carlos Bloch, Kelly Sharon M., Magalhães, M.T.Q., Sharon M. Kelly (132485), Kelly, S., Aragão, F.J.L., Bloch Jr, C., Brand Guilherme D., Aragão Francisco J. L., Maria L. P. Tinoco (132476), Magalhães Mariana T. Q., Alan Cooper, Bloch Carlos, Cooper, A., Mariana T Q Magalhães, Nicoli Jacques, Carlos Bloch Jr (132488)   +31 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Phenotypic profile and molecular mechanism of resistance in carbapenemase-producing Enterobacterales and Pseudomonas aeruginosa isolates from Brazilian hospitals: implications for the introduction of imipenem-relebactam

Frontiers in Microbiology
Background/ObjectivesCarbapenemase-producing Enterobacterales and P. aeruginosa are critical threats to global public health, especially in high-burden regions such as Brazil.
Pedro Kurtz, Pedro Kurtz, Pedro F. Del Peloso, Bruno Rocha Pribul, Arthur M. Albuquerque, Bianca B. P. Antunes, Grazielle Vianna Ramos, Fernando A. Bozza, Fernando A. Bozza, Fernando A. Bozza   +9 more
doaj   +1 more source

Clinical Observation of Low-Temperature Plasma Ablation Combined with Drug Therapy in the Treatment of Fungal Keratitis

Infection and Drug Resistance, 2023
Tao Sun,1– 4 Bo-Wen Zhang,1– 4 Rui Xiong,1– 4 Wen-Tian Zhou,1– 4 Jing-Jing Qiu5 1Affiliated Eye Hospital of Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 2Jiangxi Clinical Research Center for Ophthalmic Disease, Nanchang ...
Sun T, Zhang BW, Xiong R, Zhou WT, Qiu JJ   +4 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Globicatella sanguinis—A Literature Review of Case Reports

Medicina
Globicatella sanguinis is a rare and distinct Gram-positive coccus, first described in 1992, and part of the normal human microbiota. Although infrequent, it can cause serious infections such as urinary tract infections, meningitis, and endocarditis ...
Carmen Valerica Rîpă, Roxana Gabriela Cobzaru, Luminita Smaranda Iancu, Miruna Raluca Rîpă, Gabriela Popescu, Alexandra Maștaleru, Andra Oancea, Maria Magdalena Leon   +7 more
doaj   +1 more source

Global burden of bacterial antimicrobial resistance 1990-2021: a systematic analysis with forecasts to 2050 [PDF]

Background: Antimicrobial resistance (AMR) poses an important global health challenge in the 21st century. A previous study has quantified the global and regional burden of AMR for 2019, followed with additional publications that provided more detailed ...
GBD, 2021 Antimicrobial Resistance Collaborators, GBD 2021 Antimicrobial Resistance Collaborators   +1 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source