PLoS Pathogens, 2010 The inability of sodium antimony gluconate (SAG)-unresponsive kala-azar patients to clear Leishmania donovani (LD) infection despite SAG therapy is partly due to an ill-defined immune-dysfunction.
Arun Kumar Haldar +8 more
doaj +5 more sources
Combination Therapy with Indolylquinoline Derivative and Sodium Antimony Gluconate Cures Established Visceral Leishmaniasis in Hamsters [PDF]
Antimicrobial Agents and Chemotherapy, 2002 ABSTRACT 2-(2″-Dichloroacetamidobenzyl)-3-(3′-indolylquinoline), designated indolylquinoline derivative A, reduced the splenic and the liver parasite burdens by >93.0% in Leishmania donovani -infected hamsters, whereas sodium antimony gluconate (SAG) reduced the burdens approximately 80.0%.
Chiranjib Pal +2 more
exaly +4 more sources
Retraction: Leishmania donovani isolates with antimony-resistant but not -sensitive phenotype inhibit sodium antimony gluconate-induced dendritic cell activation. [PDF]
PLoS PathogPLOS Pathogens Editors.
europepmc +6 more sources
Combination Therapy Using Sodium Antimony Gluconate in Stearylamine-Bearing Liposomes against Established and ChronicLeishmania donovaniInfection in BALB/c Mice [PDF]
Antimicrobial Agents and Chemotherapy, 2004 ABSTRACTIn this work we report the activity seen with combination therapy using sodium antimony gluconate in liposomes composed of egg phosphatidyl choline and stearylamine for elimination ofLeishmania donovaniparasites from the liver and spleen of BALB/c mice with established and chronic infections.
Swati, Pal +2 more
openaire +3 more sources
Journal of Pathology of Nepal, 2017 Leishmaniasis is considered to be zoonotic disease, caused by a protozoan parasite of the genus Leishmania, and transmitted by a bite of infected female sandfly.
Ram Chandra Adhikari, Mahesh Shah
doaj +3 more sources
Parasites & Vectors, 2014 Background Visceral leishmaniasis (VL), also called Kala Azar (KA) or black fever in India, claims around 20,000 lives every year. Chemotherapy remains one of the most important tools in the control of VL.
Neeloo Singh +2 more
doaj +2 more sources
Bulletin of the World Health Organization, 2001 OBJECTIVE: To compare the use of generic and proprietary sodium stibogluconate for the treatment of visceral leishmaniasis (kala-azar). METHODS: A total of 102 patients with confirmed kala-azar were treated in a mission hospital in West Pokot region ...
Moore Elinore +6 more
doaj +2 more sources
Leishmaniasis with secondary hemophagocytic syndrome: a case report [PDF]
Zhenduanxue lilun yu shijian, 2022 Leishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors.
XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
doaj +1 more source
Nanoarchitectonics of Porous Carbons Templated by Inorganic Metal Oxides and Alkali Metal Salts for Energy and Environmental Applications. [PDF]
Adv Sci (Weinh)This review explores inorganic metal oxides and metal salt nanoparticles templated porous carbons, highlighting their synthesis, structural features, and performance in energy and environmental applications. It critically compares template types, porosity control, and functional outcomes across recent literature.
Singh G +8 more
europepmc +2 more sources
Antimony susceptible Leishmania donovani: evidence from in vitro drug susceptibility of parasites isolated from patients of post-kala-azar dermal leishmaniasis in pre- and post-miltefosine era. [PDF]
Microbiol SpectrPost-kala-azar dermal leishmaniasis (PKDL) patients are a key source of Leishmania donovani parasites, hindering the goal of eliminating visceral leishmaniasis (VL). Monitoring treatment response and parasite susceptibility is essential due to increasing
Ghosh S +6 more
europepmc +2 more sources