Results 51 to 60 of about 2,821 (202)
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith +2 more
wiley +1 more source
Jörg Krebs,1 Jürgen Pannek,2,3 Franziska Rademacher,2 Jens Wöllner2 1Clinical Trial Unit, Swiss Paraplegic Centre, Nottwil, Switzerland; 2Neuro-Urology, Swiss Paraplegic Centre, Nottwil, Switzerland; 3Department of Urology, Inselspital ...
Krebs J +3 more
doaj
Background: The pharmacological treatment of urinary incontinence (UI) may involve bladder antimuscarinics, which can generate risks in the elderly. Objective: The aim was to determine the treatment patterns of a group of patients with UI and possible ...
Luis Fernando Valladales-Restrepo +3 more
doaj +1 more source
Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu +7 more
wiley +1 more source
Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives
Dudley Robinson, Miriam O’Kane, Linda Cardozo Department of Urogynaecology, King’s College Hospital, London, UKCorrespondence: Dudley Robinson, Department of Urogynaecology, King’s College Hospital, Suite 8, Level 3, Golden Jubilee Wing, London, SE5 9RS,
Robinson D, O'Kane M, Cardozo L
doaj
According to the International Continence Society (ICS), symptoms of overactive bladder (OAB) are present in 17 % of the adult population of Europe.
O. I. Ivakhnenko +4 more
doaj +1 more source
The black line is the overall DDD of antimuscarinics for each year. The dotted line is the trendline of linear regression test.
Ling-Ying Wu (7470542) +6 more
core +1 more source
Cardiovascular Risk in Users of Mirabegron Compared with Users of Antimuscarinic Treatments for Overactive Bladder:Findings from a Non-Interventional, Multinational, Cohort Study [PDF]
Introduction: During clinical trials, mirabegron, a β3-adrenoreceptor agonist, was associated with increased vital signs vs placebo in patients with overactive bladder.
Horter, Libby +26 more
core +1 more source
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza +12 more
wiley +1 more source
Objective To understand factors guiding overactive bladder (OAB) therapy selection and experience with combination therapy (antimuscarinics and beta-3 agonists).
Stephen R. Kraus +6 more
doaj +1 more source

