Drug-induced male infertility: a real-world study using FAERS and EudraVigilance databases [PDF]
ObjectiveTo systematically identify medications potentially causing male infertility or sperm abnormalities and provide risk alerts for clinical practice.MethodsA pharmacovigilance study was conducted using the FAERS database (Q1 2004–Q2 2025) and ...
Zhuozhi Gong +4 more
doaj +2 more sources
Cytotoxic Activity of Antineoplastic Agents on Fertility: A Systematic Review [PDF]
Objective: To analyze the long-term effects of antineoplastic treatments on patient fertility. Selection of Studies: The studies were selected through the New PubMed, Scielo and Lilacs databases along with references used for the creation of the present
Gabriel Acácio de Moura +1 more
doaj +1 more source
Epidemiological profile of COVID-19 in patients with prostate cancer undergoing androgen deprivation therapy at a Brazilian Cancer Center [PDF]
Objective To describe the epidemiological aspects of COVID-19 in patients with prostate cancer who received androgen deprivation therapy and those who did not.
Isabela Granato Travalini +6 more
doaj +1 more source
Background and Objectives: Ovarian surgical ablation (OSA) in estrogen receptor-positive (ER+) breast cancer is usually performed to halt ovarian function in premenopausal patients.
Joana Correia Oliveira +3 more
doaj +1 more source
Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1 [PDF]
The purine anti-metabolite 6-mercaptopurine is one of the most widely used drugs for the treatment of acute childhood leukemia and chronic myelocytic leukemia. Developed in the 1950s, the drug is also being used as a treatment for inflammatory diseases such as Crohn's disease. The antiproliferative mechanism of action of this drug and other purine anti-
Peter, Ordentlich +3 more
openaire +2 more sources
The seventieth anniversary of the hormonal treatment of prostatic carcinoma [PDF]
Hormonal treatment of prostatic carcinoma was initiated in the first half of twentieth century. Theoretical basis of hormonal treatment was established with the work of Charles Brenton Huggins published in 1941.
Milovanović Lela
doaj +1 more source
Primary endocrine therapy of locally advanced breast cancer patients [PDF]
Primary endocrine therapy has been traditionally reserved for elderly and unfit locally advanced breast cancer patients (LABC patients). In this group, the primary endocrine therapy could not be adequately compared to primary chemotherapy.
Nešković-Konstantinović Zora B.
doaj +1 more source
EO771, the first luminal B mammary cancer cell line from C57BL/6 mice
Background Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatment and to understand the prognosis
Augustin Le Naour +11 more
doaj +1 more source
Treatment of metastatic breast cancer with anastrozole in patients previously treated with aminoglutethimide - case report [PDF]
Anastrozole represents new, strong and selective nonsteroid aromatase inhibitor. The purpose of this report was to show the effect of anastrozole in two patients with breast cancer who were previously treated with aminoglutethimide. A female patient aged
Boškov Nedeljka
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