Results 161 to 170 of about 1,663,582 (244)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Reproductive and sexual sequelae of neuroendocrine tumour therapies: an under-recognised challenge. [PDF]

Endocr Relat Cancer
Shekhda KM, Shah PM, Biddanda A, Grossman A, Caplin M.   +4 more
europepmc   +1 more source

Long‐term endurance running training and testosterone daily variation in ageing men; a comparative cross‐sectional study

Experimental Physiology, EarlyView.
Abstract The aim of this study was to assess the relationship between long‐term endurance running training and daily variation in testosterone, which is known to diminish during ageing, in a comparative, cross‐sectional study. We recruited 45 male participants into four groups [young athletes (YA), young sedentary (YS), master athletes (MA) and elderly
Barbora Bartko, Ľudmila Oreská, Gabriel Buzgó, Genc Berisha, Valentína Zemaníková, Monika Okuliarová, Michal Zeman, Milan Sedliak   +7 more
wiley   +1 more source

Reply to Venkataraman, J.; Mokbel, K. Reconsidering the Interpretation of "Recurrence-Free Survival" After Mastectomy for DCIS. Comment on "Sae-sim et al. Tamoxifen Reduces Breast Cancer Recurrence in Women with DCIS Who Underwent Mastectomy. <i>Curr. Oncol</i>. 2026, <i>33</i>, 89". [PDF]

Curr Oncol
Sae-Sim N, Samarnthai N, Numprasit W.
europepmc   +1 more source

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

Experimental Physiology, EarlyView.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto, Shigekazu Takemura, Yukiko Minamiyama, Toshikazu Yoshikawa   +3 more
wiley   +1 more source

Clinical characteristics, management, and prognosis of ipilimumab-induced hypophysitis: a retrospective analysis of 76 cases. [PDF]

Front Endocrinol (Lausanne)
Wu L, Yang Y, Su Q.
europepmc   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

A Rare Paediatric Adrenocortical Carcinoma with Aggressive Clinical Course. [PDF]

J ASEAN Fed Endocr Soc
Lim KY, Tee PP.
europepmc   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Enzalutamide Monotherapy for the Treatment of Prostate Cancer With High-Risk Biochemical Recurrence: EMBARK Secondary End Points. [PDF]

J Urol
Shore ND, De Giorgi U, Tutrone RF, Bailen JL, Roos EPM, Kliment J, Marx G, Karsh LI, Ramirez-Backhaus M, Uchio EM, Supiot S, Tang Y, Rosbrook B, Haas GP, Rosales M, Zohren F, Tarazi J, Freedland SJ.   +17 more
europepmc   +1 more source