Results 161 to 170 of about 13,105 (210)

Oviductus Ranae as a Functional Food for Ovary Protection: Ameliorating Premature Ovarian Failure and Modulating PI3K/Akt and Apoptosis Pathways in Rats

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic illustration of the experimental design for evaluating the protective effects of Oviductus Ranae (OR) against cyclophosphamide (CTX)‐induced premature ovarian failure (POF) in rats. Female Wistar rats were intraperitoneally injected with CTX (100 mg/kg on Day 0, followed by 10 mg/kg daily) for 14–16 days to establish the POF model.
Hongyu Zhao   +6 more
wiley   +1 more source

Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 1, Page 257-268, 1 July 2026.
What's New? Epithelial ovarian cancer (EOC) is a severe malignancy with few effective treatment options. While the mechanisms remain unclear, changes in lipid metabolism may fuel tumor growth and EOC progression, offering a possible path for new treatments.
Hitomi Sakaguchi‐Mukaida   +10 more
wiley   +1 more source

2‐Pyrazoline‐5‐One Derivative Suppresses Cell Proliferation and Induces Apoptosis With Upregulation of Bax in Breast Cancer Cells

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
2‐Pyrazoline‐5‐one derivative inhibits proliferation and migration and induces Bax‐mediated apoptosis in breast cancer cells. ABSTRACT The most common cancer in women worldwide is still breast cancer. Among its subtypes, luminal A and triple‐negative breast cancers present significant therapeutic challenges due to intrinsic drug resistance and absence ...
Sevgi Kocyigit Sevinc   +3 more
wiley   +1 more source

Exosome Secretion Drives Chemo‐Resistance of Temozolomide in Glioblastoma

open access: yesJournal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Temozolomide (TMZ) is a first‐line chemotherapeutic agent for the treatment of glioblastoma (GBM), while a majority of patients do not effectively respond to TMZ owing to the multiple resistance mechanisms. In this study, we found that TMZ treatment substantially increased the exosome secretion from GBM cell line.
Wenpei Li   +9 more
wiley   +1 more source

Trends in the Dispensing of Oral Anti-Cancer Medications Across Australia Over 10 Years. [PDF]

open access: yesPharmacoepidemiol Drug Saf
Leach MJ   +5 more
europepmc   +1 more source

Recycling of hazelnut waste: Antidiabetic properties of soy lecithin nanoparticles and their in vitro anti‐proliferative effects in tumor cell lines

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5596-5613, July 2026.
Abstract BACKGROUND Hazelnuts and foods produced using hazelnuts are consumed with pleasure, but it is important to evaluate the waste generated during hazelnut processing and determine their usage methods. RESULTS This study was conducted to determine the changes in bioactive components, bioaccessibility and antidiabetic activity of nanoparticles ...
Mehmet Ali Temiz, Emine Okumus
wiley   +1 more source

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