Results 131 to 140 of about 3,367,527 (366)
Acute cardiac toxicity of antineoplastic agents as the first manifestation of pheochromocytoma [PDF]
, 1978 Diosdado N. Deasis +3 more
openalex +1 more source
Advanced Chinese Medicine, EarlyView.Abstract The tumor microenvironment (TME) plays a pivotal role in tumorigenesis and metastasis, with cancer‐associated fibroblasts (CAFs) and neutrophil extracellular traps (NETs) identified as key contributors to its dynamic regulation. This review elucidates the multifaceted roles of CAFs and NETs in tumor progression and clarifies their intricate ...
Jiangbo Chen +5 more
wiley +1 more source
Synergistic Effect of Angelica gigas and Saccharin on Antiproliferative Activity in Ovcar-3 Cells
Korean Journal of Clinical Laboratory ScienceMany patients with ovarian epithelial cancer, which accounts for more than 90% of ovarian cancers, are resistant to chemotherapy. Accordingly, Eastern medicine, which uses natural products as medicines, has been proposed.
Sang Yong PARK +5 more
doaj +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
, 2020 Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
Experimental pharmacological research regarding some new quinazolin-4-ones derivatives [PDF]
, 2019 A series of new compounds with quinazolin-4-one structure, synthesized by the Pharmaceutical Chemistry Department of the Faculty of Pharmacy of the University of Medicine and Pharmacy “Carol Davila” Bucharest, was studied.
Bratu, Mihaela +8 more
core +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Journal for ImmunoTherapy of CancerBackground Despite immunization, patients on antineoplastic and immunomodulating agents have a heightened risk of COVID-19 infection. However, accurately attributing this risk to specific medications remains challenging.Methods An observational cohort ...
Ki Suk Eum +16 more
doaj +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, EarlyView.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Advanced Engineering Materials, EarlyView.Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez +2 more
wiley +1 more source