Results 141 to 150 of about 210,920 (352)

Managing Pharmacotherapy in People Living With HIV and Concomitant Malignancy. [PDF]

, 2019
Objective: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of ...
Chan, Alexandre, Klibanov, Olga, Olin, Jacqueline L, Spooner, Linda M   +3 more
core   +1 more source

An agent framework for dynamic agent retraining: Agent academy [PDF]

In B. Stanford-Smith, E. Chiozza, and M. Edin, editors, Challenges and Achievements in e-business and e-work, pages 757-764, Prague, Czech Republic, October 2002. IOS Press, 2004
Agent Academy (AA) aims to develop a multi-agent society that can train new agents for specific or general tasks, while constantly retraining existing agents in a recursive mode. The system is based on collecting information both from the environment and the behaviors of the acting agents and their related successes/failures to generate a body of data,
arxiv  

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

The gut microbiota during tamoxifen therapy in patients with breast cancer

Scientific Reports
Tamoxifen is essential in treating estrogen receptor-positive (ER+) breast cancer, primarily through its active metabolite, endoxifen. Emerging research suggests potential interactions between tamoxifen and gut microbiota.
Lars E. Hillege, David J. M. Barnett, Janine Ziemons, Romy Aarnoutse, Judith de Vos-Geelen, Robin van Geel, Maaike de Boer, Yvonne E. A. van Riet, Jeroen Vincent, John Penders, Marjolein L. Smidt   +10 more
doaj   +1 more source

Agent TCP/IP: An Agent-to-Agent Transaction System [PDF]

arXiv
Autonomous agents represent an inevitable evolution of the internet. Current agent frameworks do not embed a standard protocol for agent-to-agent interaction, leaving existing agents isolated from their peers. As intellectual property is the native asset ingested by and produced by agents, a true agent economy requires equipping agents with a universal
arxiv  

An informational study of the evolution of codes and of emerging concepts in populations of agents [PDF]

arXiv, 2015
We consider the problem of the evolution of a code within a structured population of agents. The agents try to maximise their information about their environment by acquiring information from the outputs of other agents in the population. A naive use of information-theoretic methods would assume that every agent knows how to "interpret" the information
arxiv  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Development of a Multi-Agent System for Optimal Sizing of a Commercial Complex Microgrid [PDF]

arXiv, 2018
In this paper, a novel intelligent method based on a multi-agent system (MAS) is applied to the problem of optimal sizing in a stand-alone office complex microgrid such that the electricity demand of the office building and the charging demand of the plug-in hybrid electric vehicle (PHEV) charging station are met.
arxiv  

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia. [PDF]

Sci Rep, 2023
Vitale C, Griggio V, Todaro M, Riganti C, Jones R, Boccellato E, Perutelli F, Arruga F, Vaisitti T, Efremov DG, Deaglio S, Landesman Y, Bruno B, Coscia M.   +13 more
europepmc   +1 more source